Matches in SemOpenAlex for { <https://semopenalex.org/work/W4253445067> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4253445067 endingPage "61" @default.
- W4253445067 startingPage "54" @default.
- W4253445067 abstract "The term anaphylaxis was coined by Charles Richet and Paul Portier when they tried to immunize dogs with actinia extracts, but after a repeated injection of a small amount of the toxin the dog died within 25 min. The new term rapidly spread all over the world. The discovery of the phenomenon of anaphylaxis showed that by immunization not only protection but also harmful events could be induced. For this discovery Richet received the Nobel Prize in 1913, but he still believed the condition of anaphylaxis was a lack of protection to the poisonous effect of the substance. Already earlier similar clinical phenomena had been observed but not well described. A major breakthrough in understanding the pathophysiology came through the experiments of Dale and Laidlaw who showed that the newly discovered histamine was able to induce quite similar symptoms to anaphylaxis. For decades reactions mimicking anaphylaxis but without involvement of the immune systems were called ‘anaphylactoid', ‘allergy-like' or ‘pseudo-allergic'. Since the new definition of the World Allergy Organization (WAO) anaphylaxis is defined on the basis of clinical symptoms independent of pathomechanisms involved: one distinguishes between allergic and non-immune anaphylaxis. Epinephrine (Adrenalin) was soon recognized as treatment of choice of this dramatic condition." @default.
- W4253445067 created "2022-05-12" @default.
- W4253445067 creator A5014484985 @default.
- W4253445067 creator A5023280808 @default.
- W4253445067 creator A5045962356 @default.
- W4253445067 creator A5090012430 @default.
- W4253445067 date "2014-01-01" @default.
- W4253445067 modified "2023-10-18" @default.
- W4253445067 title "Anaphylaxis" @default.
- W4253445067 doi "https://doi.org/10.1159/000358503" @default.
- W4253445067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24925384" @default.
- W4253445067 hasPublicationYear "2014" @default.
- W4253445067 type Work @default.
- W4253445067 citedByCount "22" @default.
- W4253445067 countsByYear W42534450672014 @default.
- W4253445067 countsByYear W42534450672015 @default.
- W4253445067 countsByYear W42534450672016 @default.
- W4253445067 countsByYear W42534450672017 @default.
- W4253445067 countsByYear W42534450672018 @default.
- W4253445067 countsByYear W42534450672020 @default.
- W4253445067 countsByYear W42534450672021 @default.
- W4253445067 countsByYear W42534450672022 @default.
- W4253445067 countsByYear W42534450672023 @default.
- W4253445067 crossrefType "book-chapter" @default.
- W4253445067 hasAuthorship W4253445067A5014484985 @default.
- W4253445067 hasAuthorship W4253445067A5023280808 @default.
- W4253445067 hasAuthorship W4253445067A5045962356 @default.
- W4253445067 hasAuthorship W4253445067A5090012430 @default.
- W4253445067 hasBestOaLocation W42534450671 @default.
- W4253445067 hasConcept C1122143 @default.
- W4253445067 hasConcept C203014093 @default.
- W4253445067 hasConcept C207480886 @default.
- W4253445067 hasConcept C2775859304 @default.
- W4253445067 hasConcept C2775933838 @default.
- W4253445067 hasConcept C42219234 @default.
- W4253445067 hasConcept C71924100 @default.
- W4253445067 hasConcept C98274493 @default.
- W4253445067 hasConceptScore W4253445067C1122143 @default.
- W4253445067 hasConceptScore W4253445067C203014093 @default.
- W4253445067 hasConceptScore W4253445067C207480886 @default.
- W4253445067 hasConceptScore W4253445067C2775859304 @default.
- W4253445067 hasConceptScore W4253445067C2775933838 @default.
- W4253445067 hasConceptScore W4253445067C42219234 @default.
- W4253445067 hasConceptScore W4253445067C71924100 @default.
- W4253445067 hasConceptScore W4253445067C98274493 @default.
- W4253445067 hasLocation W42534450671 @default.
- W4253445067 hasLocation W42534450672 @default.
- W4253445067 hasOpenAccess W4253445067 @default.
- W4253445067 hasPrimaryLocation W42534450671 @default.
- W4253445067 hasRelatedWork W1659709475 @default.
- W4253445067 hasRelatedWork W2007512646 @default.
- W4253445067 hasRelatedWork W2307896020 @default.
- W4253445067 hasRelatedWork W2416437643 @default.
- W4253445067 hasRelatedWork W2507193333 @default.
- W4253445067 hasRelatedWork W2762943905 @default.
- W4253445067 hasRelatedWork W3005698903 @default.
- W4253445067 hasRelatedWork W3107687923 @default.
- W4253445067 hasRelatedWork W3216567778 @default.
- W4253445067 hasRelatedWork W4210399498 @default.
- W4253445067 isParatext "false" @default.
- W4253445067 isRetracted "false" @default.
- W4253445067 workType "book-chapter" @default.