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- W4253702004 abstract "Abstract One of the properties of the immune system that makes it different from nervous and en-docrine systems of mammals is the ability of immune cells to migrate between different tissues. Lymphocytes such as T and B cells have the ability to migrate from the blood to secondary lymphoid tissues such as spleen, lymph nodes, and Peyer’s patches, and then migrate back to the blood, i.e., they can recirculate. Recirculation of lymphocytes has been a subject of intensive investigation decades ago with wealth of data on the kinetics of lymphocyte recirculation available. However, these data have not been widely used to estimate the kinetics of recirculation of different lymphocyte subsets in naive and immunized animals. In this paper we review pioneering studies addressing the question of lymphocyte recirculation, overview quantitative approaches that have been used to estimate the kinetics of lymphocyte recirculation, and provide currently published estimates of the residence times of resting lymphocytes in secondary lymphoid tissues of mammals." @default.
- W4253702004 created "2022-05-12" @default.
- W4253702004 creator A5005587295 @default.
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- W4253702004 date "2018-02-22" @default.
- W4253702004 modified "2023-10-16" @default.
- W4253702004 title "Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes" @default.
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- W4253702004 doi "https://doi.org/10.1101/268326" @default.
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