Matches in SemOpenAlex for { <https://semopenalex.org/work/W4253708410> ?p ?o ?g. }
- W4253708410 endingPage "e564" @default.
- W4253708410 startingPage "e558" @default.
- W4253708410 abstract "Sarcomas are a rare group of malignant tumors of mesenchymal origin that comprise 1% of all adult cancers. Despite initial surgery, distant metastatic disease will develop in approximately 25% of patients, and standard chemotherapy has limited durable efficacy. There is a dire need for more effective and less toxic therapies for the treatment of metastatic sarcoma. The immune system plays a major role in cancer control and progression. There have been tremendous breakthroughs in other malignancies by manipulating the immune system with checkpoint inhibitors. These agents, either alone or in combination with other approaches such as radiation, chemotherapy, targeted agents, or immunotherapeutics, have generally led to improved efficacy in selected malignancies thus far. Although promising, these drugs can cause specific immune-related adverse events that require prompt recognition and treatment. In addition, characterizing response and progression radiographically has become somewhat more challenging. Identifying predictive biomarkers of benefit will be essential. There remains optimism and hope that the strides made in other cancers will be emulated in sarcoma." @default.
- W4253708410 created "2022-05-12" @default.
- W4253708410 creator A5089731384 @default.
- W4253708410 date "2016-05-01" @default.
- W4253708410 modified "2023-09-26" @default.
- W4253708410 title "Manipulating the Immune System With Checkpoint Inhibitors for Patients With Metastatic Sarcoma" @default.
- W4253708410 cites W1509070276 @default.
- W4253708410 cites W1637579675 @default.
- W4253708410 cites W1973913634 @default.
- W4253708410 cites W1980241157 @default.
- W4253708410 cites W1980715318 @default.
- W4253708410 cites W1990675339 @default.
- W4253708410 cites W2003950027 @default.
- W4253708410 cites W2009487870 @default.
- W4253708410 cites W2011435623 @default.
- W4253708410 cites W2011850791 @default.
- W4253708410 cites W2019607817 @default.
- W4253708410 cites W2022873825 @default.
- W4253708410 cites W2025300117 @default.
- W4253708410 cites W2029855686 @default.
- W4253708410 cites W2041873469 @default.
- W4253708410 cites W2048073154 @default.
- W4253708410 cites W2049553585 @default.
- W4253708410 cites W2066671159 @default.
- W4253708410 cites W2070059266 @default.
- W4253708410 cites W2081070412 @default.
- W4253708410 cites W2081447339 @default.
- W4253708410 cites W2081613982 @default.
- W4253708410 cites W2083139200 @default.
- W4253708410 cites W2087013294 @default.
- W4253708410 cites W2087482409 @default.
- W4253708410 cites W2087792479 @default.
- W4253708410 cites W2100158834 @default.
- W4253708410 cites W2106631163 @default.
- W4253708410 cites W2107752337 @default.
- W4253708410 cites W2109653150 @default.
- W4253708410 cites W2111415894 @default.
- W4253708410 cites W2112121482 @default.
- W4253708410 cites W2113170011 @default.
- W4253708410 cites W2121071739 @default.
- W4253708410 cites W2123363005 @default.
- W4253708410 cites W2128758225 @default.
- W4253708410 cites W2133075384 @default.
- W4253708410 cites W2134281922 @default.
- W4253708410 cites W2134724142 @default.
- W4253708410 cites W2143163879 @default.
- W4253708410 cites W2150678612 @default.
- W4253708410 cites W2160834915 @default.
- W4253708410 cites W2162466652 @default.
- W4253708410 cites W2411664162 @default.
- W4253708410 cites W4232939899 @default.
- W4253708410 doi "https://doi.org/10.1200/edbk_161901" @default.
- W4253708410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27249767" @default.
- W4253708410 hasPublicationYear "2016" @default.
- W4253708410 type Work @default.
- W4253708410 citedByCount "8" @default.
- W4253708410 countsByYear W42537084102016 @default.
- W4253708410 countsByYear W42537084102017 @default.
- W4253708410 countsByYear W42537084102018 @default.
- W4253708410 countsByYear W42537084102019 @default.
- W4253708410 countsByYear W42537084102020 @default.
- W4253708410 countsByYear W42537084102021 @default.
- W4253708410 crossrefType "journal-article" @default.
- W4253708410 hasAuthorship W4253708410A5089731384 @default.
- W4253708410 hasConcept C121608353 @default.
- W4253708410 hasConcept C126322002 @default.
- W4253708410 hasConcept C142724271 @default.
- W4253708410 hasConcept C143998085 @default.
- W4253708410 hasConcept C197934379 @default.
- W4253708410 hasConcept C203014093 @default.
- W4253708410 hasConcept C2776694085 @default.
- W4253708410 hasConcept C2777701055 @default.
- W4253708410 hasConcept C2778256501 @default.
- W4253708410 hasConcept C2779134260 @default.
- W4253708410 hasConcept C2780851360 @default.
- W4253708410 hasConcept C502942594 @default.
- W4253708410 hasConcept C509974204 @default.
- W4253708410 hasConcept C71924100 @default.
- W4253708410 hasConcept C8891405 @default.
- W4253708410 hasConceptScore W4253708410C121608353 @default.
- W4253708410 hasConceptScore W4253708410C126322002 @default.
- W4253708410 hasConceptScore W4253708410C142724271 @default.
- W4253708410 hasConceptScore W4253708410C143998085 @default.
- W4253708410 hasConceptScore W4253708410C197934379 @default.
- W4253708410 hasConceptScore W4253708410C203014093 @default.
- W4253708410 hasConceptScore W4253708410C2776694085 @default.
- W4253708410 hasConceptScore W4253708410C2777701055 @default.
- W4253708410 hasConceptScore W4253708410C2778256501 @default.
- W4253708410 hasConceptScore W4253708410C2779134260 @default.
- W4253708410 hasConceptScore W4253708410C2780851360 @default.
- W4253708410 hasConceptScore W4253708410C502942594 @default.
- W4253708410 hasConceptScore W4253708410C509974204 @default.
- W4253708410 hasConceptScore W4253708410C71924100 @default.
- W4253708410 hasConceptScore W4253708410C8891405 @default.
- W4253708410 hasIssue "36" @default.
- W4253708410 hasLocation W42537084101 @default.
- W4253708410 hasLocation W42537084102 @default.
- W4253708410 hasOpenAccess W4253708410 @default.