Matches in SemOpenAlex for { <https://semopenalex.org/work/W4253774975> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W4253774975 endingPage "v" @default.
- W4253774975 startingPage "v" @default.
- W4253774975 abstract "Following systemic inflammation, the lung induces an isoenzyme of heme oxygenase (HO-1), catalyzing carbon monoxide (CO) production through breakdown of heme molecules. However, it is still debated why the paradoxical arterio-venous carboxyhemoglobin (COHb) difference occurs only during critical illness but not in healthy volunteers. To elucidate whether oxygen fractions at (sub-)physiologic ranges alter the affinity of CO to hemoglobin (Hb), we performed an in vitro laboratory experiment, in which we exposed venous blood samples to fixed CO-doses at incrementing oxygen fractions (FiO2). ANOVA demonstrated that the affinity of CO (200 and 400 ppm) to Hb progressively increased with an FiO2 from 0% to 15%, whereas at higher oxygen tensions this effect vanished. This might explain why the arterio-venous COHb difference found in critically ill patients is not reproducible in healthy adults, since the latter ones are characterized by higher venous oxygen saturations." @default.
- W4253774975 created "2022-05-12" @default.
- W4253774975 date "2002-09-01" @default.
- W4253774975 modified "2023-09-25" @default.
- W4253774975 title "Author Index" @default.
- W4253774975 doi "https://doi.org/10.1016/s0006-291x(02)02208-8" @default.
- W4253774975 hasPublicationYear "2002" @default.
- W4253774975 type Work @default.
- W4253774975 citedByCount "0" @default.
- W4253774975 crossrefType "journal-article" @default.
- W4253774975 hasConcept C104317684 @default.
- W4253774975 hasConcept C126322002 @default.
- W4253774975 hasConcept C161790260 @default.
- W4253774975 hasConcept C178790620 @default.
- W4253774975 hasConcept C181199279 @default.
- W4253774975 hasConcept C185592680 @default.
- W4253774975 hasConcept C2776217839 @default.
- W4253774975 hasConcept C2776378800 @default.
- W4253774975 hasConcept C2778917026 @default.
- W4253774975 hasConcept C2779219270 @default.
- W4253774975 hasConcept C42219234 @default.
- W4253774975 hasConcept C43044207 @default.
- W4253774975 hasConcept C512735826 @default.
- W4253774975 hasConcept C540031477 @default.
- W4253774975 hasConcept C55493867 @default.
- W4253774975 hasConcept C71924100 @default.
- W4253774975 hasConcept C86339819 @default.
- W4253774975 hasConcept C98270193 @default.
- W4253774975 hasConceptScore W4253774975C104317684 @default.
- W4253774975 hasConceptScore W4253774975C126322002 @default.
- W4253774975 hasConceptScore W4253774975C161790260 @default.
- W4253774975 hasConceptScore W4253774975C178790620 @default.
- W4253774975 hasConceptScore W4253774975C181199279 @default.
- W4253774975 hasConceptScore W4253774975C185592680 @default.
- W4253774975 hasConceptScore W4253774975C2776217839 @default.
- W4253774975 hasConceptScore W4253774975C2776378800 @default.
- W4253774975 hasConceptScore W4253774975C2778917026 @default.
- W4253774975 hasConceptScore W4253774975C2779219270 @default.
- W4253774975 hasConceptScore W4253774975C42219234 @default.
- W4253774975 hasConceptScore W4253774975C43044207 @default.
- W4253774975 hasConceptScore W4253774975C512735826 @default.
- W4253774975 hasConceptScore W4253774975C540031477 @default.
- W4253774975 hasConceptScore W4253774975C55493867 @default.
- W4253774975 hasConceptScore W4253774975C71924100 @default.
- W4253774975 hasConceptScore W4253774975C86339819 @default.
- W4253774975 hasConceptScore W4253774975C98270193 @default.
- W4253774975 hasIssue "1" @default.
- W4253774975 hasLocation W42537749751 @default.
- W4253774975 hasOpenAccess W4253774975 @default.
- W4253774975 hasPrimaryLocation W42537749751 @default.
- W4253774975 hasRelatedWork W115512639 @default.
- W4253774975 hasRelatedWork W1499045336 @default.
- W4253774975 hasRelatedWork W1539391634 @default.
- W4253774975 hasRelatedWork W1858073635 @default.
- W4253774975 hasRelatedWork W1973657530 @default.
- W4253774975 hasRelatedWork W2004329815 @default.
- W4253774975 hasRelatedWork W2017676913 @default.
- W4253774975 hasRelatedWork W2044386194 @default.
- W4253774975 hasRelatedWork W2047461810 @default.
- W4253774975 hasRelatedWork W323833488 @default.
- W4253774975 hasVolume "297" @default.
- W4253774975 isParatext "false" @default.
- W4253774975 isRetracted "false" @default.
- W4253774975 workType "article" @default.