FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4253783492> ?p ?o ?g. }

• W4253783492 abstract "Abstract Background Total mesorectal excision (TME) with or without neoadjuvant concurrent chemoradiotherapy (CCRT) is the treatment for rectal cancer (RC). Recently, the use of conventional laparoscopic surgery (LS) or robotic-assisted surgery (RS) has been on a steady increase cases. However, various oncological outcomes from different surgical approaches are still under investigation.Materials and methods This is a retrospective observational study comprising 300 consecutive RC patients who underwent various techniques of TME (RS, n = 88; LS, n = 37; Open surgery, n = 175) at a single center of real world data to compare the pathological and oncological outcomes, with a median follow-up of 48 months.Results Upon multivariate analysis, histologic grade ( P =0.048), tumor depth ( P =0.003), and pre-operative CCRT ( P =0.038) were the independent factors of circumferential resection margin (CRM) involvement. The Kaplan-Meier survival analysis determined RS, early pathologic stage, negative CRM involvement, and pathologic complete response to be significantly associated with better overall survival (OS) and disease-free survival (DFS) (all P <0.05). Multivariable analyses observed the surgical method ( P =0.037), histologic grade ( P =0.006), and CRM involvement ( P =0.043) were the independent factors of DFS, whereas histologic grade ( P =0.011) and pathologic stage ( P =0.022) were the independent prognostic variables of OS.Conclusions This study determined that RS TME is feasible because it has less CRM involvement and better oncological outcomes than the alternatives have. The significant factors influencing CRM and prognosis depended on the histologic grade, tumor depth, and pre-operative CCRT. RS might be an acceptable option owing to the favorable oncological outcomes for patients with RC undergoing TME." @default.
• W4253783492 created "2022-05-12" @default.
• W4253783492 creator A5008262587 @default.
• W4253783492 creator A5009015283 @default.
• W4253783492 creator A5015428672 @default.
• W4253783492 creator A5020320585 @default.
• W4253783492 creator A5047472928 @default.
• W4253783492 creator A5048995161 @default.
• W4253783492 creator A5053604127 @default.
• W4253783492 creator A5071886010 @default.
• W4253783492 date "2020-01-02" @default.
• W4253783492 modified "2023-10-16" @default.
• W4253783492 title "An observational study of patho-oncological outcomes of various surgical methods in total mesorectal excision for rectal cancer: a single center analysis" @default.
• W4253783492 cites W1523782391 @default.
• W4253783492 cites W1926888387 @default.
• W4253783492 cites W1976314895 @default.
• W4253783492 cites W2002971944 @default.
• W4253783492 cites W2010999690 @default.
• W4253783492 cites W2017132889 @default.
• W4253783492 cites W2019054694 @default.
• W4253783492 cites W2023582529 @default.
• W4253783492 cites W2034048092 @default.
• W4253783492 cites W2046779549 @default.
• W4253783492 cites W2047298950 @default.
• W4253783492 cites W2065970530 @default.
• W4253783492 cites W2067827673 @default.
• W4253783492 cites W2077536567 @default.
• W4253783492 cites W2077582039 @default.
• W4253783492 cites W2104029004 @default.
• W4253783492 cites W2106014206 @default.
• W4253783492 cites W2109001225 @default.
• W4253783492 cites W2131073034 @default.
• W4253783492 cites W2312491311 @default.
• W4253783492 cites W2315138336 @default.
• W4253783492 cites W2319588241 @default.
• W4253783492 cites W2325438728 @default.
• W4253783492 cites W2331936925 @default.
• W4253783492 cites W2332134529 @default.
• W4253783492 cites W2407266212 @default.
• W4253783492 cites W2560322684 @default.
• W4253783492 cites W2588006464 @default.
• W4253783492 cites W2593080634 @default.
• W4253783492 cites W2759032239 @default.
• W4253783492 cites W2763074632 @default.
• W4253783492 cites W2774609230 @default.
• W4253783492 cites W2792536175 @default.
• W4253783492 cites W2800124507 @default.
• W4253783492 cites W2891873444 @default.
• W4253783492 cites W2982594172 @default.
• W4253783492 cites W3013851657 @default.
• W4253783492 doi "https://doi.org/10.21203/rs.2.17091/v2" @default.
• W4253783492 hasPublicationYear "2020" @default.
• W4253783492 type Work @default.
• W4253783492 citedByCount "0" @default.
• W4253783492 crossrefType "posted-content" @default.
• W4253783492 hasAuthorship W4253783492A5008262587 @default.
• W4253783492 hasAuthorship W4253783492A5009015283 @default.
• W4253783492 hasAuthorship W4253783492A5015428672 @default.
• W4253783492 hasAuthorship W4253783492A5020320585 @default.
• W4253783492 hasAuthorship W4253783492A5047472928 @default.
• W4253783492 hasAuthorship W4253783492A5048995161 @default.
• W4253783492 hasAuthorship W4253783492A5053604127 @default.
• W4253783492 hasAuthorship W4253783492A5071886010 @default.
• W4253783492 hasBestOaLocation W42537834921 @default.
• W4253783492 hasConcept C121608353 @default.
• W4253783492 hasConcept C126322002 @default.
• W4253783492 hasConcept C141071460 @default.
• W4253783492 hasConcept C143998085 @default.
• W4253783492 hasConcept C146357865 @default.
• W4253783492 hasConcept C151730666 @default.
• W4253783492 hasConcept C167135981 @default.
• W4253783492 hasConcept C207886595 @default.
• W4253783492 hasConcept C23131810 @default.
• W4253783492 hasConcept C2777201421 @default.
• W4253783492 hasConcept C2778292576 @default.
• W4253783492 hasConcept C2778424827 @default.
• W4253783492 hasConcept C2778913397 @default.
• W4253783492 hasConcept C2780073493 @default.
• W4253783492 hasConcept C2780091936 @default.
• W4253783492 hasConcept C3019894029 @default.
• W4253783492 hasConcept C38180746 @default.
• W4253783492 hasConcept C526805850 @default.
• W4253783492 hasConcept C530470458 @default.
• W4253783492 hasConcept C71924100 @default.
• W4253783492 hasConcept C86803240 @default.
• W4253783492 hasConceptScore W4253783492C121608353 @default.
• W4253783492 hasConceptScore W4253783492C126322002 @default.
• W4253783492 hasConceptScore W4253783492C141071460 @default.
• W4253783492 hasConceptScore W4253783492C143998085 @default.
• W4253783492 hasConceptScore W4253783492C146357865 @default.
• W4253783492 hasConceptScore W4253783492C151730666 @default.
• W4253783492 hasConceptScore W4253783492C167135981 @default.
• W4253783492 hasConceptScore W4253783492C207886595 @default.
• W4253783492 hasConceptScore W4253783492C23131810 @default.
• W4253783492 hasConceptScore W4253783492C2777201421 @default.
• W4253783492 hasConceptScore W4253783492C2778292576 @default.
• W4253783492 hasConceptScore W4253783492C2778424827 @default.
• W4253783492 hasConceptScore W4253783492C2778913397 @default.
• W4253783492 hasConceptScore W4253783492C2780073493 @default.
• W4253783492 hasConceptScore W4253783492C2780091936 @default.

• next