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- W4253982519 endingPage "1805" @default.
- W4253982519 startingPage "1796" @default.
- W4253982519 abstract "Using a genetic assay for efficient autonomous replication, we have isolated from Schizosaccharomyces pombe a 6.2-kb fragment which shows the properties expected of an origin of DNA replication in S. pombe. A 2.8-kb subclone of the fragment has the same replication properties. Two-dimensional gel analysis of replication intermediates throughout plasmids carrying the 6.2- or 2.8-kb fragments shows that replication initiates only in a specific region, which can be localized to within several hundred base pairs, in the fragments. This region is also a site of replication initiation in the S. pombe chromosome where the fragments normally reside. These results provide strong evidence that initiation of replication in S. pombe is localized and mediated by specific DNA sequence signals." @default.
- W4253982519 created "2022-05-12" @default.
- W4253982519 creator A5045200104 @default.
- W4253982519 creator A5073515972 @default.
- W4253982519 date "1994-03-01" @default.
- W4253982519 modified "2023-10-17" @default.
- W4253982519 title "Specific initiation at an origin of replication from Schizosaccharomyces pombe" @default.
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- W4253982519 doi "https://doi.org/10.1128/mcb.14.3.1796-1805.1994" @default.
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