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- W4253997621 abstract "The tremendous advances in size-exclusion column technology in the last decade have resulted in an order of magnitude reduction in analysis times in gel-permeation chromatography (GPC) since the technique was first introduced in the 1960's. The availability of highly efficient (up to 50,000 plates/meter) columns containing a broad pore-size distribution has enabled many separations to be performed using a single column, with no loss of resolution. The more recent development of 5-µm polystyrene-divinylbenzene gel packings has resulted in capabilities for oligomer separations which were unheard of just a few years ago. As GPC separations are performed in less time, with fewer columns, the performance of other components of the chromatographic system becomes critical. A well-designed system for high-resolution, high speed GPC should embody precise control of flow rate and column temperature, minimal peak-broadening effects from both extra-column sources and the columns themselves, and sophisticated data acquisition and processing. The separation of oligomers is an application which clearly demonstrates the advantages of a systems approach to high-resolution, high-speed GPC." @default.
- W4253997621 created "2022-05-12" @default.
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- W4253997621 date "1984-03-30" @default.
- W4253997621 modified "2023-10-10" @default.
- W4253997621 title "High-Performance High-Speed Gel Permeation Chromatography" @default.
- W4253997621 doi "https://doi.org/10.1021/bk-1984-0245.ch012" @default.
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