Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254039069> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W4254039069 endingPage "2086" @default.
- W4254039069 startingPage "2086" @default.
- W4254039069 abstract "The purpose of this study was to determine the effects of chronic moderate and heavy ethanol consumption on myocardial ischemia/reperfusion injury. Three groups (n = 18) of 6-month-old female Sprague-Dawley rats were fed a nutritionally balanced liquid diet. Control, moderate alcohol, and heavy alcohol groups consumed 0%, 20%, and 35% of their calories from ethanol, respectively. After 10 weeks of feeding, hearts were isolated and subjected to 21.5 min of ischemia alone, or 21.5 min of ischemia followed by 30 min reperfusion. Hearts were evaluated for hemodynamic characteristics and high-energy phosphate content. Hearts from animals exposed to moderate and heavy amounts of ethanol recovered significantly less (30.61% and 29.45%, respectively) of their preischemic cardiac external work than control hearts (65.52%). Postischemic diastolic stiffness was increased ˜7-fold, and high-energy phosphate content, both creatine phosphate and adenosine triphosphate, decreased >25% by both chronic moderate and heavy ethanol consumption. In conclusion, both chronic moderate and heavy ethanol consumption exacerbate myocardial ischemia/reperfusion injury. The ethanol-induced reduction in postischemic energy status may be the mechanism of increased diastolic stiffness and subsequent reduced cardiac external work." @default.
- W4254039069 created "2022-05-12" @default.
- W4254039069 creator A5052933117 @default.
- W4254039069 creator A5063248134 @default.
- W4254039069 creator A5074943810 @default.
- W4254039069 creator A5087017857 @default.
- W4254039069 date "1998-12-01" @default.
- W4254039069 modified "2023-09-23" @default.
- W4254039069 title "Effects of Chronic Moderate and Heavy Ethanol Consumption on Myocardial Recovery from Ischemia" @default.
- W4254039069 doi "https://doi.org/10.1097/00000374-199812000-00027" @default.
- W4254039069 hasPublicationYear "1998" @default.
- W4254039069 type Work @default.
- W4254039069 citedByCount "0" @default.
- W4254039069 crossrefType "journal-article" @default.
- W4254039069 hasAuthorship W4254039069A5052933117 @default.
- W4254039069 hasAuthorship W4254039069A5063248134 @default.
- W4254039069 hasAuthorship W4254039069A5074943810 @default.
- W4254039069 hasAuthorship W4254039069A5087017857 @default.
- W4254039069 hasConcept C126322002 @default.
- W4254039069 hasConcept C134018914 @default.
- W4254039069 hasConcept C164705383 @default.
- W4254039069 hasConcept C178853913 @default.
- W4254039069 hasConcept C185592680 @default.
- W4254039069 hasConcept C2779896295 @default.
- W4254039069 hasConcept C2780114680 @default.
- W4254039069 hasConcept C2780161600 @default.
- W4254039069 hasConcept C40438245 @default.
- W4254039069 hasConcept C42219234 @default.
- W4254039069 hasConcept C541997718 @default.
- W4254039069 hasConcept C55493867 @default.
- W4254039069 hasConcept C57900726 @default.
- W4254039069 hasConcept C71924100 @default.
- W4254039069 hasConcept C84393581 @default.
- W4254039069 hasConceptScore W4254039069C126322002 @default.
- W4254039069 hasConceptScore W4254039069C134018914 @default.
- W4254039069 hasConceptScore W4254039069C164705383 @default.
- W4254039069 hasConceptScore W4254039069C178853913 @default.
- W4254039069 hasConceptScore W4254039069C185592680 @default.
- W4254039069 hasConceptScore W4254039069C2779896295 @default.
- W4254039069 hasConceptScore W4254039069C2780114680 @default.
- W4254039069 hasConceptScore W4254039069C2780161600 @default.
- W4254039069 hasConceptScore W4254039069C40438245 @default.
- W4254039069 hasConceptScore W4254039069C42219234 @default.
- W4254039069 hasConceptScore W4254039069C541997718 @default.
- W4254039069 hasConceptScore W4254039069C55493867 @default.
- W4254039069 hasConceptScore W4254039069C57900726 @default.
- W4254039069 hasConceptScore W4254039069C71924100 @default.
- W4254039069 hasConceptScore W4254039069C84393581 @default.
- W4254039069 hasIssue "9" @default.
- W4254039069 hasLocation W42540390691 @default.
- W4254039069 hasOpenAccess W4254039069 @default.
- W4254039069 hasPrimaryLocation W42540390691 @default.
- W4254039069 hasRelatedWork W1966223210 @default.
- W4254039069 hasRelatedWork W1996635305 @default.
- W4254039069 hasRelatedWork W2032731213 @default.
- W4254039069 hasRelatedWork W2037145429 @default.
- W4254039069 hasRelatedWork W2049439920 @default.
- W4254039069 hasRelatedWork W2058435783 @default.
- W4254039069 hasRelatedWork W2090180473 @default.
- W4254039069 hasRelatedWork W2131563031 @default.
- W4254039069 hasRelatedWork W2140217436 @default.
- W4254039069 hasRelatedWork W2378326152 @default.
- W4254039069 hasVolume "22" @default.
- W4254039069 isParatext "false" @default.
- W4254039069 isRetracted "false" @default.
- W4254039069 workType "article" @default.