Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254041182> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W4254041182 endingPage "170" @default.
- W4254041182 startingPage "159" @default.
- W4254041182 abstract "Human red blood cell concentrates with hematocrit values of 75 V% were prepared from citrate-phosphate-dextrose (CPD) blood, stored at 4 C for 20 to 28 days, and biochemically modified with a solution containing pyruvate, inosine, glucose, phosphate, and adenine (PIGPA Solution A). The rejuvenated red blood cells were frozen with 40% W/V glycerol in a polyolefin plastic bag and were stored at −80 C. After three to four years of frozen storage, the units were thawed, washed, and stored at 4 C in a sodium chloride-glucose-phosphate solution for 24 hours prior to transfusion. Red blood cell recovery was 97 per cent after thawing and 90 per cent after washing. An automated differential agglutination procedure (ADA) showed 24-hour survival values of about 80 per cent, and long-term survival values of about 85 days depending on the disease state of the recipient. The red blood cells had normal affinity for oxygen on the day of transfusion. Plasma hemoglobin levels measured immediately after transfusion indicated extravascular removal of nonviable donor red blood cells. There was no increase in the uric acid level during the 24-hour posttransfusion period. A pool of three to ten units of rejuvenated washed previously frozen red blood cells was transfused rapidly to each of 19 anemic elderly patients. The red blood cells which had normal oxygen delivery capacity immediately upon transfusion increased the recipient's red blood cell mass and produced no untoward effects." @default.
- W4254041182 created "2022-05-12" @default.
- W4254041182 creator A5004923211 @default.
- W4254041182 creator A5035155992 @default.
- W4254041182 creator A5042760025 @default.
- W4254041182 creator A5044320749 @default.
- W4254041182 creator A5049653106 @default.
- W4254041182 creator A5054187507 @default.
- W4254041182 creator A5082013577 @default.
- W4254041182 date "1980-03-01" @default.
- W4254041182 modified "2023-09-27" @default.
- W4254041182 title "Therapeutic effectiveness and safety of outdated human red blood cells rejuvenated to restore oxygen transport function to normal, frozen for 3 to 4 years at -80 C, washed, and stored at 4 C for 24 hours prior to rapid infusion" @default.
- W4254041182 doi "https://doi.org/10.1046/j.1537-2995.1980.20280169956.x" @default.
- W4254041182 hasPublicationYear "1980" @default.
- W4254041182 type Work @default.
- W4254041182 citedByCount "11" @default.
- W4254041182 countsByYear W42540411822017 @default.
- W4254041182 countsByYear W42540411822018 @default.
- W4254041182 crossrefType "journal-article" @default.
- W4254041182 hasAuthorship W4254041182A5004923211 @default.
- W4254041182 hasAuthorship W4254041182A5035155992 @default.
- W4254041182 hasAuthorship W4254041182A5042760025 @default.
- W4254041182 hasAuthorship W4254041182A5044320749 @default.
- W4254041182 hasAuthorship W4254041182A5049653106 @default.
- W4254041182 hasAuthorship W4254041182A5054187507 @default.
- W4254041182 hasAuthorship W4254041182A5082013577 @default.
- W4254041182 hasConcept C126322002 @default.
- W4254041182 hasConcept C141071460 @default.
- W4254041182 hasConcept C16685009 @default.
- W4254041182 hasConcept C179933525 @default.
- W4254041182 hasConcept C185592680 @default.
- W4254041182 hasConcept C196843134 @default.
- W4254041182 hasConcept C203014093 @default.
- W4254041182 hasConcept C2776557347 @default.
- W4254041182 hasConcept C2777208419 @default.
- W4254041182 hasConcept C2778917026 @default.
- W4254041182 hasConcept C2779881121 @default.
- W4254041182 hasConcept C2780014101 @default.
- W4254041182 hasConcept C2780920261 @default.
- W4254041182 hasConcept C2780959883 @default.
- W4254041182 hasConcept C42219234 @default.
- W4254041182 hasConcept C66112548 @default.
- W4254041182 hasConcept C71924100 @default.
- W4254041182 hasConcept C86803240 @default.
- W4254041182 hasConcept C89560881 @default.
- W4254041182 hasConcept C95444343 @default.
- W4254041182 hasConceptScore W4254041182C126322002 @default.
- W4254041182 hasConceptScore W4254041182C141071460 @default.
- W4254041182 hasConceptScore W4254041182C16685009 @default.
- W4254041182 hasConceptScore W4254041182C179933525 @default.
- W4254041182 hasConceptScore W4254041182C185592680 @default.
- W4254041182 hasConceptScore W4254041182C196843134 @default.
- W4254041182 hasConceptScore W4254041182C203014093 @default.
- W4254041182 hasConceptScore W4254041182C2776557347 @default.
- W4254041182 hasConceptScore W4254041182C2777208419 @default.
- W4254041182 hasConceptScore W4254041182C2778917026 @default.
- W4254041182 hasConceptScore W4254041182C2779881121 @default.
- W4254041182 hasConceptScore W4254041182C2780014101 @default.
- W4254041182 hasConceptScore W4254041182C2780920261 @default.
- W4254041182 hasConceptScore W4254041182C2780959883 @default.
- W4254041182 hasConceptScore W4254041182C42219234 @default.
- W4254041182 hasConceptScore W4254041182C66112548 @default.
- W4254041182 hasConceptScore W4254041182C71924100 @default.
- W4254041182 hasConceptScore W4254041182C86803240 @default.
- W4254041182 hasConceptScore W4254041182C89560881 @default.
- W4254041182 hasConceptScore W4254041182C95444343 @default.
- W4254041182 hasIssue "2" @default.
- W4254041182 hasLocation W42540411821 @default.
- W4254041182 hasOpenAccess W4254041182 @default.
- W4254041182 hasPrimaryLocation W42540411821 @default.
- W4254041182 hasRelatedWork W1990533869 @default.
- W4254041182 hasRelatedWork W2007050330 @default.
- W4254041182 hasRelatedWork W2012149199 @default.
- W4254041182 hasRelatedWork W2101921242 @default.
- W4254041182 hasRelatedWork W2122553352 @default.
- W4254041182 hasRelatedWork W2403125016 @default.
- W4254041182 hasRelatedWork W2521700667 @default.
- W4254041182 hasRelatedWork W2662633587 @default.
- W4254041182 hasRelatedWork W2958252372 @default.
- W4254041182 hasRelatedWork W4299525586 @default.
- W4254041182 hasVolume "20" @default.
- W4254041182 isParatext "false" @default.
- W4254041182 isRetracted "false" @default.
- W4254041182 workType "article" @default.