Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254082465> ?p ?o ?g. }
- W4254082465 endingPage "4472" @default.
- W4254082465 startingPage "4459" @default.
- W4254082465 abstract "In experimental autoimmune encephalomyelitis (EAE) inflammatory cells cross the endothelial blood-brain barrier (BBB) and gain access to the central nervous system (CNS). Here we show that E- and P-selectin are not involved in the recruitment of inflammatory cells across the BBB. Neither expression of E- nor P-selectin is induced in BBB-forming endothelium at any time after initiation of EAE. Some of the inflammatory cells present in the CNS during EAE express ligands for E- or P-selectin. However, anti–E- and P-selectin antibodies influence neither immigration of inflammatory cells across the BBB nor the development of EAE. In general, suppression of E- and P-selectin expression on BBB endothelium is dependent on factors derived from the CNS microenvironment, eg, astrocytes. Our results suggest that during EAE suppression of E- and P-selectin expression on the BBB provides a CNS-specific mechanism to reduce leukocyte recruitment into the CNS." @default.
- W4254082465 created "2022-05-12" @default.
- W4254082465 creator A5009450784 @default.
- W4254082465 creator A5055185080 @default.
- W4254082465 creator A5059751032 @default.
- W4254082465 creator A5069271331 @default.
- W4254082465 date "1997-12-01" @default.
- W4254082465 modified "2023-09-28" @default.
- W4254082465 title "E- and P-Selectin Are Not Involved in the Recruitment of Inflammatory Cells Across the Blood-Brain Barrier in Experimental Autoimmune Encephalomyelitis" @default.
- W4254082465 cites W1512091369 @default.
- W4254082465 cites W1514064771 @default.
- W4254082465 cites W1516595608 @default.
- W4254082465 cites W1522999898 @default.
- W4254082465 cites W1924595537 @default.
- W4254082465 cites W1974112233 @default.
- W4254082465 cites W1977940746 @default.
- W4254082465 cites W1994902496 @default.
- W4254082465 cites W1996266000 @default.
- W4254082465 cites W2003794901 @default.
- W4254082465 cites W2005701667 @default.
- W4254082465 cites W2007348558 @default.
- W4254082465 cites W2012295587 @default.
- W4254082465 cites W2022184416 @default.
- W4254082465 cites W2032371793 @default.
- W4254082465 cites W2032494769 @default.
- W4254082465 cites W2062242135 @default.
- W4254082465 cites W2076343582 @default.
- W4254082465 cites W2076634690 @default.
- W4254082465 cites W2082665551 @default.
- W4254082465 cites W2085875957 @default.
- W4254082465 cites W2087372329 @default.
- W4254082465 cites W2102440756 @default.
- W4254082465 cites W2102826458 @default.
- W4254082465 cites W2104418998 @default.
- W4254082465 cites W2107060621 @default.
- W4254082465 cites W2108617074 @default.
- W4254082465 cites W2113279573 @default.
- W4254082465 cites W2118724414 @default.
- W4254082465 cites W2123248116 @default.
- W4254082465 cites W2127534922 @default.
- W4254082465 cites W2128509983 @default.
- W4254082465 cites W2141924291 @default.
- W4254082465 cites W2143691192 @default.
- W4254082465 cites W2151221263 @default.
- W4254082465 cites W2153170677 @default.
- W4254082465 cites W2162159133 @default.
- W4254082465 cites W2162433609 @default.
- W4254082465 cites W2168210963 @default.
- W4254082465 cites W2170262191 @default.
- W4254082465 cites W2338797839 @default.
- W4254082465 doi "https://doi.org/10.1182/blood.v90.11.4459.4459_4459_4472" @default.
- W4254082465 hasPublicationYear "1997" @default.
- W4254082465 type Work @default.
- W4254082465 citedByCount "16" @default.
- W4254082465 crossrefType "journal-article" @default.
- W4254082465 hasAuthorship W4254082465A5009450784 @default.
- W4254082465 hasAuthorship W4254082465A5055185080 @default.
- W4254082465 hasAuthorship W4254082465A5059751032 @default.
- W4254082465 hasAuthorship W4254082465A5069271331 @default.
- W4254082465 hasBestOaLocation W42540824651 @default.
- W4254082465 hasConcept C134018914 @default.
- W4254082465 hasConcept C16224149 @default.
- W4254082465 hasConcept C169760540 @default.
- W4254082465 hasConcept C203014093 @default.
- W4254082465 hasConcept C2776914184 @default.
- W4254082465 hasConcept C2776992346 @default.
- W4254082465 hasConcept C2777899865 @default.
- W4254082465 hasConcept C2778402981 @default.
- W4254082465 hasConcept C2778486448 @default.
- W4254082465 hasConcept C2779835222 @default.
- W4254082465 hasConcept C2780640218 @default.
- W4254082465 hasConcept C3018697912 @default.
- W4254082465 hasConcept C529278444 @default.
- W4254082465 hasConcept C56701166 @default.
- W4254082465 hasConcept C71924100 @default.
- W4254082465 hasConcept C86803240 @default.
- W4254082465 hasConcept C89560881 @default.
- W4254082465 hasConceptScore W4254082465C134018914 @default.
- W4254082465 hasConceptScore W4254082465C16224149 @default.
- W4254082465 hasConceptScore W4254082465C169760540 @default.
- W4254082465 hasConceptScore W4254082465C203014093 @default.
- W4254082465 hasConceptScore W4254082465C2776914184 @default.
- W4254082465 hasConceptScore W4254082465C2776992346 @default.
- W4254082465 hasConceptScore W4254082465C2777899865 @default.
- W4254082465 hasConceptScore W4254082465C2778402981 @default.
- W4254082465 hasConceptScore W4254082465C2778486448 @default.
- W4254082465 hasConceptScore W4254082465C2779835222 @default.
- W4254082465 hasConceptScore W4254082465C2780640218 @default.
- W4254082465 hasConceptScore W4254082465C3018697912 @default.
- W4254082465 hasConceptScore W4254082465C529278444 @default.
- W4254082465 hasConceptScore W4254082465C56701166 @default.
- W4254082465 hasConceptScore W4254082465C71924100 @default.
- W4254082465 hasConceptScore W4254082465C86803240 @default.
- W4254082465 hasConceptScore W4254082465C89560881 @default.
- W4254082465 hasIssue "11" @default.
- W4254082465 hasLocation W42540824651 @default.
- W4254082465 hasOpenAccess W4254082465 @default.
- W4254082465 hasPrimaryLocation W42540824651 @default.