Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254088013> ?p ?o ?g. }
- W4254088013 endingPage "115" @default.
- W4254088013 startingPage "106" @default.
- W4254088013 abstract "Over the past few decades, comprehensive characterization of the cancer genome has elucidated pathways that drive cancer and mechanisms of resistance to therapy and provided important insights for development of new therapies. These advances have resulted in the development of prognostic and predictive tools for use in clinical settings, which can assist clinicians and patients in making informed decisions about the benefits of established therapies. In early-stage breast cancer, multiparameter genomic assays are now available for decision making about the duration of adjuvant endocrine therapy and the use of adjuvant chemotherapy. Similarly, in metastatic disease, there are multiple commercially available next-generation sequencing options for identifying genetic alterations in tumors that may be targeted with a drug. Although these tools hold great promise for providing precision medicine, it can be difficult for the treating physician to evaluate their clinical utility and appropriately select tools for individual clinical situations. This review summarizes the currently available genomic tools in breast cancer, the data underlying their clinical validity and utility, and how they can be used in conjunction with standard clinicopathologic data for making adjuvant and metastatic treatment decisions." @default.
- W4254088013 created "2022-05-12" @default.
- W4254088013 creator A5005537242 @default.
- W4254088013 creator A5063192858 @default.
- W4254088013 creator A5076090440 @default.
- W4254088013 date "2017-05-01" @default.
- W4254088013 modified "2023-10-16" @default.
- W4254088013 title "Standard and Genomic Tools for Decision Support in Breast Cancer Treatment" @default.
- W4254088013 cites W1528629181 @default.
- W4254088013 cites W1626477266 @default.
- W4254088013 cites W1782443628 @default.
- W4254088013 cites W1930298597 @default.
- W4254088013 cites W1948838904 @default.
- W4254088013 cites W196157878 @default.
- W4254088013 cites W1967497779 @default.
- W4254088013 cites W1975379146 @default.
- W4254088013 cites W1979330610 @default.
- W4254088013 cites W1980538358 @default.
- W4254088013 cites W2004834404 @default.
- W4254088013 cites W2009720434 @default.
- W4254088013 cites W2028846884 @default.
- W4254088013 cites W2059567292 @default.
- W4254088013 cites W2067287567 @default.
- W4254088013 cites W2096283457 @default.
- W4254088013 cites W2101881391 @default.
- W4254088013 cites W2104287359 @default.
- W4254088013 cites W2105882193 @default.
- W4254088013 cites W2106410630 @default.
- W4254088013 cites W2108456088 @default.
- W4254088013 cites W2108505891 @default.
- W4254088013 cites W2109991075 @default.
- W4254088013 cites W2111568097 @default.
- W4254088013 cites W2113344831 @default.
- W4254088013 cites W2115581335 @default.
- W4254088013 cites W2115813710 @default.
- W4254088013 cites W2118632896 @default.
- W4254088013 cites W2118728607 @default.
- W4254088013 cites W2119565091 @default.
- W4254088013 cites W2122283445 @default.
- W4254088013 cites W2126324838 @default.
- W4254088013 cites W2128196636 @default.
- W4254088013 cites W2129136620 @default.
- W4254088013 cites W2130639106 @default.
- W4254088013 cites W2130940380 @default.
- W4254088013 cites W2131398863 @default.
- W4254088013 cites W2131584282 @default.
- W4254088013 cites W2132388337 @default.
- W4254088013 cites W2133615432 @default.
- W4254088013 cites W2134133462 @default.
- W4254088013 cites W2137853125 @default.
- W4254088013 cites W2140628034 @default.
- W4254088013 cites W2144335178 @default.
- W4254088013 cites W2145777628 @default.
- W4254088013 cites W2147145576 @default.
- W4254088013 cites W2147354890 @default.
- W4254088013 cites W2147461138 @default.
- W4254088013 cites W2147828078 @default.
- W4254088013 cites W2150671673 @default.
- W4254088013 cites W2150962478 @default.
- W4254088013 cites W2151379947 @default.
- W4254088013 cites W2151726995 @default.
- W4254088013 cites W2151929173 @default.
- W4254088013 cites W2154734961 @default.
- W4254088013 cites W2156273110 @default.
- W4254088013 cites W2157434805 @default.
- W4254088013 cites W2158111334 @default.
- W4254088013 cites W2160377567 @default.
- W4254088013 cites W2160450758 @default.
- W4254088013 cites W2161977537 @default.
- W4254088013 cites W2163045991 @default.
- W4254088013 cites W2163563958 @default.
- W4254088013 cites W2166842249 @default.
- W4254088013 cites W2167926320 @default.
- W4254088013 cites W2169344399 @default.
- W4254088013 cites W2170332607 @default.
- W4254088013 cites W2172045238 @default.
- W4254088013 cites W2173858545 @default.
- W4254088013 cites W2190954851 @default.
- W4254088013 cites W2192099811 @default.
- W4254088013 cites W2247128519 @default.
- W4254088013 cites W2267844613 @default.
- W4254088013 cites W2289933199 @default.
- W4254088013 cites W2304250174 @default.
- W4254088013 cites W2314556209 @default.
- W4254088013 cites W2332880327 @default.
- W4254088013 cites W2342628598 @default.
- W4254088013 cites W2395296277 @default.
- W4254088013 cites W2396589018 @default.
- W4254088013 cites W2402051962 @default.
- W4254088013 cites W2402233591 @default.
- W4254088013 cites W2409054761 @default.
- W4254088013 cites W2409302246 @default.
- W4254088013 cites W2463462735 @default.
- W4254088013 cites W2486004214 @default.
- W4254088013 cites W2510234563 @default.
- W4254088013 cites W2517421365 @default.
- W4254088013 cites W2529908594 @default.
- W4254088013 cites W2543029979 @default.