Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254133396> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W4254133396 abstract "<p>Dynamic DNA walkers can move cargoes on a surface through various mechanisms including enzymatic reactions and strand displacement. While they have demonstrated high processivity and speed, their motion dynamics are not well understood. Here, we utilize an enzyme-powered DNA walker as a model system and adopt a random walk model to provide new insight on migration dynamics. Four distinct migration modes (ballistic, Lévy, self-avoiding, and diffusive motions) are identified. Each mode shows unique step time and velocity distributions which are related to mean squared displacement (MSD) scaling. Experimental results are in excellent agreement with the theoretical predictions. With a better understanding of the dynamics, we performed a mechanistic study, elucidating the effects of cargo types and sizes, walker sequence designs, and environmental conditions. Finally, this study provides a set of design principles for tuning the behaviors of DNA walkers. The DNA walkers from this work could serve as a versatile platform for mathematical studies and open new opportunities for bioengineering.</p>" @default.
- W4254133396 created "2022-05-12" @default.
- W4254133396 creator A5004106834 @default.
- W4254133396 creator A5029093676 @default.
- W4254133396 creator A5030614446 @default.
- W4254133396 creator A5051786018 @default.
- W4254133396 creator A5077056132 @default.
- W4254133396 date "2020-09-23" @default.
- W4254133396 modified "2023-09-29" @default.
- W4254133396 title "Mechanistic Understanding of Surface Migration Dynamics with DNA Walkers" @default.
- W4254133396 doi "https://doi.org/10.26434/chemrxiv.12991601.v1" @default.
- W4254133396 hasPublicationYear "2020" @default.
- W4254133396 type Work @default.
- W4254133396 citedByCount "0" @default.
- W4254133396 crossrefType "posted-content" @default.
- W4254133396 hasAuthorship W4254133396A5004106834 @default.
- W4254133396 hasAuthorship W4254133396A5029093676 @default.
- W4254133396 hasAuthorship W4254133396A5030614446 @default.
- W4254133396 hasAuthorship W4254133396A5051786018 @default.
- W4254133396 hasAuthorship W4254133396A5077056132 @default.
- W4254133396 hasBestOaLocation W42541333961 @default.
- W4254133396 hasConcept C105795698 @default.
- W4254133396 hasConcept C107551265 @default.
- W4254133396 hasConcept C121194460 @default.
- W4254133396 hasConcept C121332964 @default.
- W4254133396 hasConcept C121864883 @default.
- W4254133396 hasConcept C12554922 @default.
- W4254133396 hasConcept C131140672 @default.
- W4254133396 hasConcept C145912823 @default.
- W4254133396 hasConcept C15744967 @default.
- W4254133396 hasConcept C186060115 @default.
- W4254133396 hasConcept C187128312 @default.
- W4254133396 hasConcept C24890656 @default.
- W4254133396 hasConcept C2524010 @default.
- W4254133396 hasConcept C2776799497 @default.
- W4254133396 hasConcept C33923547 @default.
- W4254133396 hasConcept C41008148 @default.
- W4254133396 hasConcept C542102704 @default.
- W4254133396 hasConcept C54355233 @default.
- W4254133396 hasConcept C552990157 @default.
- W4254133396 hasConcept C59593255 @default.
- W4254133396 hasConcept C62520636 @default.
- W4254133396 hasConcept C73573662 @default.
- W4254133396 hasConcept C86803240 @default.
- W4254133396 hasConcept C99844830 @default.
- W4254133396 hasConceptScore W4254133396C105795698 @default.
- W4254133396 hasConceptScore W4254133396C107551265 @default.
- W4254133396 hasConceptScore W4254133396C121194460 @default.
- W4254133396 hasConceptScore W4254133396C121332964 @default.
- W4254133396 hasConceptScore W4254133396C121864883 @default.
- W4254133396 hasConceptScore W4254133396C12554922 @default.
- W4254133396 hasConceptScore W4254133396C131140672 @default.
- W4254133396 hasConceptScore W4254133396C145912823 @default.
- W4254133396 hasConceptScore W4254133396C15744967 @default.
- W4254133396 hasConceptScore W4254133396C186060115 @default.
- W4254133396 hasConceptScore W4254133396C187128312 @default.
- W4254133396 hasConceptScore W4254133396C24890656 @default.
- W4254133396 hasConceptScore W4254133396C2524010 @default.
- W4254133396 hasConceptScore W4254133396C2776799497 @default.
- W4254133396 hasConceptScore W4254133396C33923547 @default.
- W4254133396 hasConceptScore W4254133396C41008148 @default.
- W4254133396 hasConceptScore W4254133396C542102704 @default.
- W4254133396 hasConceptScore W4254133396C54355233 @default.
- W4254133396 hasConceptScore W4254133396C552990157 @default.
- W4254133396 hasConceptScore W4254133396C59593255 @default.
- W4254133396 hasConceptScore W4254133396C62520636 @default.
- W4254133396 hasConceptScore W4254133396C73573662 @default.
- W4254133396 hasConceptScore W4254133396C86803240 @default.
- W4254133396 hasConceptScore W4254133396C99844830 @default.
- W4254133396 hasLocation W42541333961 @default.
- W4254133396 hasLocation W42541333962 @default.
- W4254133396 hasOpenAccess W4254133396 @default.
- W4254133396 hasPrimaryLocation W42541333961 @default.
- W4254133396 hasRelatedWork W100863 @default.
- W4254133396 hasRelatedWork W11178244 @default.
- W4254133396 hasRelatedWork W1300773 @default.
- W4254133396 hasRelatedWork W1665019 @default.
- W4254133396 hasRelatedWork W3465324 @default.
- W4254133396 hasRelatedWork W6567045 @default.
- W4254133396 hasRelatedWork W7578695 @default.
- W4254133396 hasRelatedWork W82141 @default.
- W4254133396 hasRelatedWork W835659 @default.
- W4254133396 hasRelatedWork W9801447 @default.
- W4254133396 isParatext "false" @default.
- W4254133396 isRetracted "false" @default.
- W4254133396 workType "article" @default.