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- W4254142426 abstract "This chapter discusses the ethnopharmacological properties, phytochemistry, and culture conditions of the Podophyllum species. Podophyllum hexandrum (Fam. – Berberidaceae) is known as a divine drug and has been used in Ayurvedic system of medicine for treatment of ailments like constipation, colds, biliary fever, septic wounds, inflammation, burning sensation, mental disorder, monocytoid leukemia, and Hodgkin’s and non-Hodgkin’s lymphoma. Podophyllotoxin is the most active cytotoxic natural product. It is used as starting compound for the synthesis of anticancer drug etoposide and teniposide. The bioconversion of the desoxypodophyllotoxin by cell suspensions of P. hexandrum was investigated. Growth parameters of the cell suspensions were not affected by either the addition of cyclodextrin itself. When a high-frequency somatic embryogenesis was established in P. hexandrum for podophyllotoxin production, the highest podophyllotoxin accumulation was recorded in somatic embryos cultured in Murashige and Skoog medium with supplementation of sucrose." @default.
- W4254142426 created "2022-05-12" @default.
- W4254142426 date "2020-03-27" @default.
- W4254142426 modified "2023-10-18" @default.
- W4254142426 title "<scp> <i>Podophyllum</i> </scp> Species" @default.
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- W4254142426 doi "https://doi.org/10.1002/9783527825578.c02-70" @default.
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