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- W4254302018 abstract "Continuous venovenous haemofiltration is a well-established technique in the management of acute renal failure complicating the multi-organ dysfunction syndrome. In most cases this treatment is well tolerated although where lactate-buffered replacement fluids are used there is an implicit assumption that lactate is metabolised quantitatively to carbon dioxide and water. We report the case of a 46-year-old female who presented in acute renal failure requiring renal support following circulatory arrest. During lactate-buffered haemofiltration an increase in arterial lactate concentration was observed, coupled with deteriorating acid-base parameters and a decreasing cardiac output. Substitution of bicarbonate-buffered replacement fluid for lactate resulted in both the correction of the acid-base disturbance and an improvement in cardiovascular haemodynamics." @default.
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- W4254302018 date "1998-02-01" @default.
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- W4254302018 title "Lactate intolerance with continuous venovenous haemofiltration: the role of bicarbonate-buffered haemofiltration" @default.
- W4254302018 doi "https://doi.org/10.1080/714029056" @default.
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