Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254304639> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4254304639 endingPage "15" @default.
- W4254304639 startingPage "15" @default.
- W4254304639 abstract "Smokers have been found to have low exhaled nitric oxide (NO) levels. The aim of the present study was to investigate where in the respiratory system the decrease in NO occurs, and whether this decrease was affected by smoking cessation. Measurements of exhaled NO were carried out in smokers (n = 20) and non-smoking control subjects (n = 30). In nine of the smokers, exhaled NO was analysed 1, 2 and 4 weeks after smoking cessation. The level of exhaled NO at a flow rate of 0.1litre/s was significantly lower in smokers (4±2p.p.b.) than in non-smokers (7±5p.p.b.; P = 0.007). A calculation of the contributions from different areas of the lung showed that the NO flux from the airways was significantly lower (14±10 compared with 36±26nl/min; P = 0.0001) and the alveolar fraction was significantly higher (2.1±0.8 compared with 1.5±0.9p.p.b.; P = 0.006) in smokers than in non-smokers. Nine smoking subjects refrained from smoking for 4 weeks, and this resulted in increased NO flux from the airways of 28±17nl/min, which was no longer significantly different from controls. In conclusion, endogenous production of NO in the airways is decreased in smokers, but can be restored to normal values by 4 weeks after cessation of smoking. Smokers have an increased alveolar fraction of NO, and this might be a diagnostic sign of lung damage. Thus NO monitoring can be used to indicate improvements when a smoker decides to stop smoking." @default.
- W4254304639 created "2022-05-12" @default.
- W4254304639 creator A5002782249 @default.
- W4254304639 creator A5014530074 @default.
- W4254304639 creator A5017801793 @default.
- W4254304639 creator A5037422669 @default.
- W4254304639 creator A5050276153 @default.
- W4254304639 creator A5063218905 @default.
- W4254304639 creator A5073048835 @default.
- W4254304639 date "2002-07-01" @default.
- W4254304639 modified "2023-10-18" @default.
- W4254304639 title "Increased nitric oxide elimination from the airways after smoking cessation" @default.
- W4254304639 doi "https://doi.org/10.1042/cs20020004" @default.
- W4254304639 hasPublicationYear "2002" @default.
- W4254304639 type Work @default.
- W4254304639 citedByCount "14" @default.
- W4254304639 countsByYear W42543046392012 @default.
- W4254304639 countsByYear W42543046392013 @default.
- W4254304639 crossrefType "journal-article" @default.
- W4254304639 hasAuthorship W4254304639A5002782249 @default.
- W4254304639 hasAuthorship W4254304639A5014530074 @default.
- W4254304639 hasAuthorship W4254304639A5017801793 @default.
- W4254304639 hasAuthorship W4254304639A5037422669 @default.
- W4254304639 hasAuthorship W4254304639A5050276153 @default.
- W4254304639 hasAuthorship W4254304639A5063218905 @default.
- W4254304639 hasAuthorship W4254304639A5073048835 @default.
- W4254304639 hasConcept C126322002 @default.
- W4254304639 hasConcept C142724271 @default.
- W4254304639 hasConcept C2777714996 @default.
- W4254304639 hasConcept C2777843972 @default.
- W4254304639 hasConcept C2781142857 @default.
- W4254304639 hasConcept C3018587741 @default.
- W4254304639 hasConcept C3020341094 @default.
- W4254304639 hasConcept C33070731 @default.
- W4254304639 hasConcept C519581460 @default.
- W4254304639 hasConcept C534529494 @default.
- W4254304639 hasConcept C71924100 @default.
- W4254304639 hasConcept C86803240 @default.
- W4254304639 hasConcept C90924648 @default.
- W4254304639 hasConceptScore W4254304639C126322002 @default.
- W4254304639 hasConceptScore W4254304639C142724271 @default.
- W4254304639 hasConceptScore W4254304639C2777714996 @default.
- W4254304639 hasConceptScore W4254304639C2777843972 @default.
- W4254304639 hasConceptScore W4254304639C2781142857 @default.
- W4254304639 hasConceptScore W4254304639C3018587741 @default.
- W4254304639 hasConceptScore W4254304639C3020341094 @default.
- W4254304639 hasConceptScore W4254304639C33070731 @default.
- W4254304639 hasConceptScore W4254304639C519581460 @default.
- W4254304639 hasConceptScore W4254304639C534529494 @default.
- W4254304639 hasConceptScore W4254304639C71924100 @default.
- W4254304639 hasConceptScore W4254304639C86803240 @default.
- W4254304639 hasConceptScore W4254304639C90924648 @default.
- W4254304639 hasIssue "1" @default.
- W4254304639 hasLocation W42543046391 @default.
- W4254304639 hasOpenAccess W4254304639 @default.
- W4254304639 hasPrimaryLocation W42543046391 @default.
- W4254304639 hasRelatedWork W1999093211 @default.
- W4254304639 hasRelatedWork W2025402223 @default.
- W4254304639 hasRelatedWork W2060973049 @default.
- W4254304639 hasRelatedWork W2069188627 @default.
- W4254304639 hasRelatedWork W2125449963 @default.
- W4254304639 hasRelatedWork W2131638135 @default.
- W4254304639 hasRelatedWork W2409997390 @default.
- W4254304639 hasRelatedWork W2414058152 @default.
- W4254304639 hasRelatedWork W2417010377 @default.
- W4254304639 hasRelatedWork W4253743840 @default.
- W4254304639 hasVolume "103" @default.
- W4254304639 isParatext "false" @default.
- W4254304639 isRetracted "false" @default.
- W4254304639 workType "article" @default.