Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254312880> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4254312880 endingPage "364" @default.
- W4254312880 startingPage "354" @default.
- W4254312880 abstract "In rabbits (and humans), dermal BCG lesions have the same components as lesions caused by virulent tubercle bacilli, i.e., a caseous liquefied center surrounded by tuberculous granulation tissue. Therefore, BCG lesions can be used as a model in which to study the host response to this disease. In immunocompetent hosts, BCG lesions do not progress and always heal. The rate of healing of dermal BCG lesions reflected the native and acquired resistance of Lurie's susceptible and resistant inbred rabbit strains. Similarly, the rate of healing of BCG lesions has been shown to reflect the resistance to tuberculosis of human populations. However, the healing of BCG lesions in individual rabbits and humans may vary considerably from the mean. In Lurie's natively resistant rabbits, immunization with BCG was quite effective in preventing many grossly visible primary pulmonary tubercles. In his natively susceptible rabbits, BCG was hardly effective at all. In other words, the rabbits that needed it the least were helped by BCG vaccination the most, and the rabbits that needed it the most were helped the least. This principle also applies to human populations: persons with poor resistance to clinical tuberculosis would develop less immunity from BCG administration than persons with strong resistance. The efficacies of various BCG and Mycobacterium microti (the vole bacillus) vaccines were evaluated in commercial outbred rabbits by the tubercle-count method. Both of these vaccine types were effective. Recombinant BCG vaccines that contain additional antigenic components may be more promising than currently used BCG vaccines." @default.
- W4254312880 created "2022-05-12" @default.
- W4254312880 date "2014-04-30" @default.
- W4254312880 modified "2023-09-28" @default.
- W4254312880 title "Characteristics of Rabbit BCG Lesions and Efficacies of BCG and Mycobacterium microti Vaccines" @default.
- W4254312880 cites W1534839633 @default.
- W4254312880 cites W1581305040 @default.
- W4254312880 cites W1595812015 @default.
- W4254312880 cites W1967127706 @default.
- W4254312880 cites W1970841052 @default.
- W4254312880 cites W1976661884 @default.
- W4254312880 cites W1989119609 @default.
- W4254312880 cites W2017347652 @default.
- W4254312880 cites W2079288824 @default.
- W4254312880 cites W2087870908 @default.
- W4254312880 cites W2091790954 @default.
- W4254312880 cites W2106147908 @default.
- W4254312880 cites W2135565401 @default.
- W4254312880 cites W2166576258 @default.
- W4254312880 cites W2345671709 @default.
- W4254312880 cites W4233529952 @default.
- W4254312880 cites W4236842068 @default.
- W4254312880 cites W4313308970 @default.
- W4254312880 doi "https://doi.org/10.1128/9781555815684.ch23" @default.
- W4254312880 hasPublicationYear "2014" @default.
- W4254312880 type Work @default.
- W4254312880 citedByCount "0" @default.
- W4254312880 crossrefType "book-chapter" @default.
- W4254312880 hasConcept C142724271 @default.
- W4254312880 hasConcept C147483822 @default.
- W4254312880 hasConcept C159047783 @default.
- W4254312880 hasConcept C162884822 @default.
- W4254312880 hasConcept C203014093 @default.
- W4254312880 hasConcept C22070199 @default.
- W4254312880 hasConcept C2776870249 @default.
- W4254312880 hasConcept C2777975735 @default.
- W4254312880 hasConcept C2778288313 @default.
- W4254312880 hasConcept C2778497218 @default.
- W4254312880 hasConcept C2780801004 @default.
- W4254312880 hasConcept C2781069245 @default.
- W4254312880 hasConcept C523546767 @default.
- W4254312880 hasConcept C54355233 @default.
- W4254312880 hasConcept C71924100 @default.
- W4254312880 hasConcept C86803240 @default.
- W4254312880 hasConcept C89423630 @default.
- W4254312880 hasConceptScore W4254312880C142724271 @default.
- W4254312880 hasConceptScore W4254312880C147483822 @default.
- W4254312880 hasConceptScore W4254312880C159047783 @default.
- W4254312880 hasConceptScore W4254312880C162884822 @default.
- W4254312880 hasConceptScore W4254312880C203014093 @default.
- W4254312880 hasConceptScore W4254312880C22070199 @default.
- W4254312880 hasConceptScore W4254312880C2776870249 @default.
- W4254312880 hasConceptScore W4254312880C2777975735 @default.
- W4254312880 hasConceptScore W4254312880C2778288313 @default.
- W4254312880 hasConceptScore W4254312880C2778497218 @default.
- W4254312880 hasConceptScore W4254312880C2780801004 @default.
- W4254312880 hasConceptScore W4254312880C2781069245 @default.
- W4254312880 hasConceptScore W4254312880C523546767 @default.
- W4254312880 hasConceptScore W4254312880C54355233 @default.
- W4254312880 hasConceptScore W4254312880C71924100 @default.
- W4254312880 hasConceptScore W4254312880C86803240 @default.
- W4254312880 hasConceptScore W4254312880C89423630 @default.
- W4254312880 hasLocation W42543128801 @default.
- W4254312880 hasOpenAccess W4254312880 @default.
- W4254312880 hasPrimaryLocation W42543128801 @default.
- W4254312880 hasRelatedWork W1969822700 @default.
- W4254312880 hasRelatedWork W2036705442 @default.
- W4254312880 hasRelatedWork W2118211436 @default.
- W4254312880 hasRelatedWork W2151119895 @default.
- W4254312880 hasRelatedWork W2151424777 @default.
- W4254312880 hasRelatedWork W2329624450 @default.
- W4254312880 hasRelatedWork W2441934214 @default.
- W4254312880 hasRelatedWork W2735761104 @default.
- W4254312880 hasRelatedWork W392851832 @default.
- W4254312880 hasRelatedWork W4366089104 @default.
- W4254312880 isParatext "false" @default.
- W4254312880 isRetracted "false" @default.
- W4254312880 workType "book-chapter" @default.