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- W4254411446 abstract "We evaluated and compared 81 urinary tract infections (UTIs) with<i>Staphylococcus saprophyticus</i>occurring in 72 college women with<i>Escherichia coli</i>UTIs. During the 14-month study period,<i>S saprophyticus</i>was the second most common cause of UTIs, accounting for 11% of the total.<i>Staphylococcus saprophyticus</i>infections occurred more frequently during the late summer and early fall. Age, history of previous UTI, signs and symptoms of infection, and findings on urinalysis were similar in patients with<i>S saprophyticus</i>and<i>E coli</i>infections. Nine (41%) of 22<i>S saprophyticus</i>infections were localized to the upper urinary tract by the antibody-coated bacteria technique compared with 18 (16%) of 115 infections with<i>E coli</i>(<i>P</i>=.01). Rectal, vaginal, and urethral colonization with<i>S saprophyticus</i>was associated with UTI caused by these organisms, suggesting that their pathogenesis resembles that of<i>E coli</i>UTIs. In vitro susceptibility testing showed almost uniform sensitivity of<i>S saprophyticus</i>to most antimicrobials used to treat UTIs, but recurrent infections occurred in six of the 72 women despite adequate therapy. Physicians and microbiologists must be aware that<i>S saprophyticus</i>is an important cause of UTIs in young women. (<i>JAMA</i>1983;250:3063-3066)" @default.
- W4254411446 created "2022-05-12" @default.
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- W4254411446 date "1983-12-09" @default.
- W4254411446 modified "2023-10-16" @default.
- W4254411446 title "Urinary tract infections in young adult women caused by Staphylococcus saprophyticus" @default.
- W4254411446 doi "https://doi.org/10.1001/jama.250.22.3063" @default.
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