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- W4254455684 abstract "Abstract We demonstrate a fluid–fluid phase separation in 1,2‐dimyristoyl‐ sn ‐glycero‐3‐phosphocholine (DMPC) membranes using a metal complex lipid of type [Mn(L1)] ( 1 ; HL1=1‐(2‐hydroxybenzamide)‐2‐(2‐hydroxy‐3‐formyl‐5‐hexadecyloxybenzylideneamino)ethane). Small amount of 1 produces two separated domains in DMPC, whose phase transition temperatures of lipids ( T c ) are both lower than that of the pristine DMPC. Variable temperature fluorescent microscopy for giant‐unilamellar vesicles of DMPC/ 1 hybrids demonstrates that visible phase separations remain in fluid phases up to 37 °C, which is clearly over the T c of DMPC. This provides a new dimension for the application of metal complex lipids toward controlling lipid distributions in fluid membranes." @default.
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- W4254455684 date "2021-05-06" @default.
- W4254455684 modified "2023-10-15" @default.
- W4254455684 title "Metal Complex Lipids for Fluid–Fluid Phase Separation in Coassembled Phospholipid Membranes" @default.
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- W4254455684 doi "https://doi.org/10.1002/ange.202102774" @default.
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