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- W4254505849 endingPage "63" @default.
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- W4254505849 abstract "Except for an essential step for the pathology of multiple diseases including atherosclerosis and rheumatoid arthritis, inflammation is an imperative therapeutic target for developing novel approaches for pharmacological interventions. Thus, a molecular understanding of inflammation not only provides a venue for knowledge that reveals the mechanisms of drug action and their biological targets, but also has spawned innovative maneuvers to influence multifaceted biological systems from different levels, providing new prospects for drug design and suggesting important new implications for existing clinical medicine. Meanwhile, the modulation of inflammation with the use of medicinal plants proposes an alternate to conventional therapeutic strategies for numerous ailments, particularly when suppression of inflammation is expected. Given that the mechanisms of insult in these disorders are facilitated by manipulating immune responses, it is factual to assume that the natural sources used for such illnesses may alleviate the immune signals and the subsequent inflammation. In the modern literature, several species of medicinal plants have been shown to have substantial antiinflammatory and immunomodulatory actions, including inhibitory effects on the suppression of cellular and humoral immunity, lymphocyte activation, and propagation of apoptosis. Herein, we review the molecular pharmacology and signaling pathways of inflammation, the chemical components and biological activities of medicinal plants, and their mechanism of action during inflammation at the molecular level. An extensive review of the literature and electronic databases was conducted, encompassing PubMed, Google Scholar, and ScienceDirect to assemble the information." @default.
- W4254505849 created "2022-05-12" @default.
- W4254505849 creator A5017090030 @default.
- W4254505849 creator A5046597133 @default.
- W4254505849 date "2021-01-01" @default.
- W4254505849 modified "2023-10-01" @default.
- W4254505849 title "Molecular pharmacology of inflammation: Medicinal plants as antiinflammatory agents" @default.
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