FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254663917> ?p ?o ?g. }

• W4254663917 endingPage "1019" @default.
• W4254663917 startingPage "1014" @default.
• W4254663917 abstract "We have analysed 174 gastric carcinomas from the United Kingdom and from Japan for the presence of Epstein-Barr virus (EBV) using in situ hybridisation for the small EBV-encoded nuclear RNAs (EBERs). EBV was detected in the tumour cells in all of six undifferentiated gastric carcinomas with prominent lymphoid stroma (undifferentiated carcinomas of nasopharyngeal type, UCNT) but only in three of the remaining 168 typical gastric adenocarcinomas (1.8%). No differences were observed between the British and the Japanese cases. One case with an EBV-positive UCNT showed adjacent areas of EBV-negative typical adenocarcinoma. It is uncertain whether these patterns represent two independent carcinomas or whether they are the result of heterogeneous EBV infection in a single tumour. In the remaining EBV-positive carcinomas, viral transcripts were detected in virtually all tumour cells, indicating that EBV infection must have taken place early in the neoplastic process and suggesting that the virus is likely to be of pathogenetic significance for the virus-associated tumours. Immunohistology demonstrated absence of detectable levels of the EBV-encoded latent membrane protein, LMP1, and nuclear antigen, EBNA2. The BZLF1 protein which induces the switch from latent to lytic infection was demonstrated in a small proportion of the tumour cells in three cases. The close association of EBV with undifferentiated gastric carcinomas compared to the variable association with gastric adenocarcinomas suggests fundamentally different roles for the virus in the aetiology of these two malignancies." @default.
• W4254663917 created "2022-05-12" @default.
• W4254663917 creator A5001898602 @default.
• W4254663917 creator A5008302290 @default.
• W4254663917 creator A5012145455 @default.
• W4254663917 creator A5012470161 @default.
• W4254663917 creator A5022165504 @default.
• W4254663917 creator A5036846181 @default.
• W4254663917 creator A5041389613 @default.
• W4254663917 creator A5041465210 @default.
• W4254663917 creator A5044837722 @default.
• W4254663917 creator A5052044654 @default.
• W4254663917 creator A5056801490 @default.
• W4254663917 date "1993-11-01" @default.
• W4254663917 modified "2023-10-16" @default.
• W4254663917 title "Epstein-Barr virus and carcinomas: rare association of the virus with gastric adenocarcinomas" @default.
• W4254663917 doi "https://doi.org/10.1038/bjc.1993.472" @default.
• W4254663917 hasPublicationYear "1993" @default.
• W4254663917 type Work @default.
• W4254663917 citedByCount "77" @default.
• W4254663917 countsByYear W42546639172013 @default.
• W4254663917 countsByYear W42546639172014 @default.
• W4254663917 countsByYear W42546639172015 @default.
• W4254663917 countsByYear W42546639172017 @default.
• W4254663917 countsByYear W42546639172019 @default.
• W4254663917 countsByYear W42546639172020 @default.
• W4254663917 countsByYear W42546639172021 @default.
• W4254663917 countsByYear W42546639172022 @default.
• W4254663917 countsByYear W42546639172023 @default.
• W4254663917 crossrefType "journal-article" @default.
• W4254663917 hasAuthorship W4254663917A5001898602 @default.
• W4254663917 hasAuthorship W4254663917A5008302290 @default.
• W4254663917 hasAuthorship W4254663917A5012145455 @default.
• W4254663917 hasAuthorship W4254663917A5012470161 @default.
• W4254663917 hasAuthorship W4254663917A5022165504 @default.
• W4254663917 hasAuthorship W4254663917A5036846181 @default.
• W4254663917 hasAuthorship W4254663917A5041389613 @default.
• W4254663917 hasAuthorship W4254663917A5041465210 @default.
• W4254663917 hasAuthorship W4254663917A5044837722 @default.
• W4254663917 hasAuthorship W4254663917A5052044654 @default.
• W4254663917 hasAuthorship W4254663917A5056801490 @default.
• W4254663917 hasBestOaLocation W42546639171 @default.
• W4254663917 hasConcept C121608353 @default.
• W4254663917 hasConcept C126322002 @default.
• W4254663917 hasConcept C142724271 @default.
• W4254663917 hasConcept C147483822 @default.
• W4254663917 hasConcept C159047783 @default.
• W4254663917 hasConcept C182615771 @default.
• W4254663917 hasConcept C203014093 @default.
• W4254663917 hasConcept C2522874641 @default.
• W4254663917 hasConcept C2776409557 @default.
• W4254663917 hasConcept C2778847070 @default.
• W4254663917 hasConcept C2778997737 @default.
• W4254663917 hasConcept C2780727368 @default.
• W4254663917 hasConcept C2781182431 @default.
• W4254663917 hasConcept C2781295983 @default.
• W4254663917 hasConcept C2781375147 @default.
• W4254663917 hasConcept C509974204 @default.
• W4254663917 hasConcept C54355233 @default.
• W4254663917 hasConcept C71924100 @default.
• W4254663917 hasConcept C86803240 @default.
• W4254663917 hasConceptScore W4254663917C121608353 @default.
• W4254663917 hasConceptScore W4254663917C126322002 @default.
• W4254663917 hasConceptScore W4254663917C142724271 @default.
• W4254663917 hasConceptScore W4254663917C147483822 @default.
• W4254663917 hasConceptScore W4254663917C159047783 @default.
• W4254663917 hasConceptScore W4254663917C182615771 @default.
• W4254663917 hasConceptScore W4254663917C203014093 @default.
• W4254663917 hasConceptScore W4254663917C2522874641 @default.
• W4254663917 hasConceptScore W4254663917C2776409557 @default.
• W4254663917 hasConceptScore W4254663917C2778847070 @default.
• W4254663917 hasConceptScore W4254663917C2778997737 @default.
• W4254663917 hasConceptScore W4254663917C2780727368 @default.
• W4254663917 hasConceptScore W4254663917C2781182431 @default.
• W4254663917 hasConceptScore W4254663917C2781295983 @default.
• W4254663917 hasConceptScore W4254663917C2781375147 @default.
• W4254663917 hasConceptScore W4254663917C509974204 @default.
• W4254663917 hasConceptScore W4254663917C54355233 @default.
• W4254663917 hasConceptScore W4254663917C71924100 @default.
• W4254663917 hasConceptScore W4254663917C86803240 @default.
• W4254663917 hasIssue "5" @default.
• W4254663917 hasLocation W42546639171 @default.
• W4254663917 hasLocation W42546639172 @default.
• W4254663917 hasLocation W42546639173 @default.
• W4254663917 hasLocation W42546639174 @default.
• W4254663917 hasOpenAccess W4254663917 @default.
• W4254663917 hasPrimaryLocation W42546639171 @default.
• W4254663917 hasRelatedWork W196628130 @default.
• W4254663917 hasRelatedWork W2062539457 @default.
• W4254663917 hasRelatedWork W2065251836 @default.
• W4254663917 hasRelatedWork W2103324672 @default.
• W4254663917 hasRelatedWork W2165501580 @default.
• W4254663917 hasRelatedWork W2407585420 @default.
• W4254663917 hasRelatedWork W2767420145 @default.
• W4254663917 hasRelatedWork W2916965814 @default.
• W4254663917 hasRelatedWork W3149007021 @default.
• W4254663917 hasRelatedWork W3175832157 @default.
• W4254663917 hasVolume "68" @default.

• next