FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254703726> ?p ?o ?g. }

• W4254703726 endingPage "1024" @default.
• W4254703726 startingPage "1016" @default.
• W4254703726 abstract "The objective of this randomized multicenter trial was to assess the prophylactic effect on the incidence and severity of the first variceal hemorrhage of endoscopic sclerotherapy, propranolol and the combination of the two compared with none of these treatments in patients with cirrhosis and esophageal varices. Among 819 cirrhotic patients who never had experienced variceal bleeding, esophagoscopy revealed varices in 379, of whom 286 were enrolled in the trial; 73 were allocated to sclerotherapy (paravenous polidocanol [10 mg/ml] every 1 to 2 wk until eradication), 68 to propranolol (slow-release preparation in one daily dose adjusted to provide about 25% heart rate reduction), 73 to both treatments and 72 to neither of the two treatments. The patients were observed for up to 42 mo, with an average of 15 mo. After variceal bleeding, patients in all groups received sclerotherapy only. The incidences of variceal bleeding (n = 50) were almost identical in the four groups. The relative risk (with 95% confidence limits) with sclerotherapy was 1.06 (0.61 to 1.84), and the relative risk with propranolol was 0.92 (0.53 to 1.60). The mortality rate after variceal bleeding (n = 29) did not differ significantly either. The mortality rate without variceal bleeding (n = 46) was 2.75 (1.45 to 5.22) times higher in the sclerotherapy groups than in the nonsclerotherapy groups (p = 0.002), whereas propranolol showed no effect, the relative risk being 1.17 (0.66 to 2.10). The total mortality rate showed no significant difference between the sclerotherapy, propranolol and control groups, but the combined therapy group had a significantly increased mortality rate. This trial yielded evidence against prophylaxis of variceal hemorrhage in cirrhosis by endoscopic sclerosing injections, with or without propranolol, and no support of propranolol used alone. HEPATOLOGY 1991;14:000–000.)" @default.
• W4254703726 created "2022-05-12" @default.
• W4254703726 date "1991-12-01" @default.
• W4254703726 modified "2023-10-02" @default.
• W4254703726 title "Prophylaxis of first hemorrhage from esophageal varices by sclerotherapy, propranolol or both in cirrhotic patients: A randomized multicenter trial" @default.
• W4254703726 cites W1498357895 @default.
• W4254703726 cites W1554641506 @default.
• W4254703726 cites W1582378906 @default.
• W4254703726 cites W1775295856 @default.
• W4254703726 cites W1968239929 @default.
• W4254703726 cites W1985990956 @default.
• W4254703726 cites W1990693343 @default.
• W4254703726 cites W1995932670 @default.
• W4254703726 cites W2009177756 @default.
• W4254703726 cites W2010551207 @default.
• W4254703726 cites W2013256551 @default.
• W4254703726 cites W2013499640 @default.
• W4254703726 cites W2014331949 @default.
• W4254703726 cites W2028024203 @default.
• W4254703726 cites W2038252730 @default.
• W4254703726 cites W2040553060 @default.
• W4254703726 cites W2041055738 @default.
• W4254703726 cites W2081755385 @default.
• W4254703726 cites W2084921997 @default.
• W4254703726 cites W2087686895 @default.
• W4254703726 cites W2103194760 @default.
• W4254703726 cites W2108579436 @default.
• W4254703726 cites W2154593257 @default.
• W4254703726 cites W2157354106 @default.
• W4254703726 cites W2162754437 @default.
• W4254703726 cites W2162812223 @default.
• W4254703726 cites W2328498131 @default.
• W4254703726 cites W2338827637 @default.
• W4254703726 cites W2341325695 @default.
• W4254703726 cites W2408578678 @default.
• W4254703726 cites W2795638792 @default.
• W4254703726 cites W3025344055 @default.
• W4254703726 cites W4235352480 @default.
• W4254703726 doi "https://doi.org/10.1002/hep.1840140612" @default.
• W4254703726 hasPublicationYear "1991" @default.
• W4254703726 type Work @default.
• W4254703726 citedByCount "47" @default.
• W4254703726 countsByYear W42547037262012 @default.
• W4254703726 countsByYear W42547037262015 @default.
• W4254703726 countsByYear W42547037262018 @default.
• W4254703726 countsByYear W42547037262020 @default.
• W4254703726 countsByYear W42547037262021 @default.
• W4254703726 countsByYear W42547037262022 @default.
• W4254703726 countsByYear W42547037262023 @default.
• W4254703726 crossrefType "journal-article" @default.
• W4254703726 hasConcept C126322002 @default.
• W4254703726 hasConcept C141071460 @default.
• W4254703726 hasConcept C15451672 @default.
• W4254703726 hasConcept C168563851 @default.
• W4254703726 hasConcept C2777214474 @default.
• W4254703726 hasConcept C2777595160 @default.
• W4254703726 hasConcept C2778012290 @default.
• W4254703726 hasConcept C2778151854 @default.
• W4254703726 hasConcept C2778230777 @default.
• W4254703726 hasConcept C2778808290 @default.
• W4254703726 hasConcept C2780950165 @default.
• W4254703726 hasConcept C44249647 @default.
• W4254703726 hasConcept C71924100 @default.
• W4254703726 hasConcept C82789193 @default.
• W4254703726 hasConcept C90924648 @default.
• W4254703726 hasConceptScore W4254703726C126322002 @default.
• W4254703726 hasConceptScore W4254703726C141071460 @default.
• W4254703726 hasConceptScore W4254703726C15451672 @default.
• W4254703726 hasConceptScore W4254703726C168563851 @default.
• W4254703726 hasConceptScore W4254703726C2777214474 @default.
• W4254703726 hasConceptScore W4254703726C2777595160 @default.
• W4254703726 hasConceptScore W4254703726C2778012290 @default.
• W4254703726 hasConceptScore W4254703726C2778151854 @default.
• W4254703726 hasConceptScore W4254703726C2778230777 @default.
• W4254703726 hasConceptScore W4254703726C2778808290 @default.
• W4254703726 hasConceptScore W4254703726C2780950165 @default.
• W4254703726 hasConceptScore W4254703726C44249647 @default.
• W4254703726 hasConceptScore W4254703726C71924100 @default.
• W4254703726 hasConceptScore W4254703726C82789193 @default.
• W4254703726 hasConceptScore W4254703726C90924648 @default.
• W4254703726 hasIssue "6" @default.
• W4254703726 hasLocation W42547037261 @default.
• W4254703726 hasOpenAccess W4254703726 @default.
• W4254703726 hasPrimaryLocation W42547037261 @default.
• W4254703726 hasRelatedWork W1498357895 @default.
• W4254703726 hasRelatedWork W1979286248 @default.
• W4254703726 hasRelatedWork W1993935922 @default.
• W4254703726 hasRelatedWork W2010435757 @default.
• W4254703726 hasRelatedWork W2413191903 @default.
• W4254703726 hasRelatedWork W2416051505 @default.
• W4254703726 hasRelatedWork W2770813585 @default.
• W4254703726 hasRelatedWork W2958165163 @default.
• W4254703726 hasRelatedWork W4302307268 @default.
• W4254703726 hasRelatedWork W4311795684 @default.
• W4254703726 hasVolume "14" @default.
• W4254703726 isParatext "false" @default.
• W4254703726 isRetracted "false" @default.
• W4254703726 workType "article" @default.