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- W4254753324 abstract "Chronic allergen exposure drives T follicular helper cell (TFH) formation in the lung draining lymph node after 1 week and the lung tissue after 3 weeks TFH at both sites interact with germinal centre B cells and are critical for the production of allergen specific IgE Allergic disease is also hallmarked by cellular inflammation and airway hyperresponsiveness driven by IL-13 Blocking ICOS and ICOS-L interactions between TFH and B cells reduces allergen specific IgE production and also dampens other hallmark symptoms of allergic airway disease" @default.
- W4254753324 created "2022-05-12" @default.
- W4254753324 date "2019-04-01" @default.
- W4254753324 modified "2023-10-16" @default.
- W4254753324 doi "https://doi.org/10.1111/all.2019.74.issue-4" @default.
- W4254753324 hasPublicationYear "2019" @default.
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