FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4254787592> ?p ?o ?g. }

• W4254787592 abstract "Antiplatelet therapy may attenuate the undesirable effects of platelets on the inflammatory cascades in critical illness. The objective of this study was to evaluate the association between aspirin therapy during intensive care unit (ICU) stay and all-cause mortality. This was a nested cohort study within two randomized controlled trials in which all enrolled patients (N = 763) were grouped according to aspirin intake during ICU stay. The primary endpoints were all-cause ICU mortality and hospital mortality. Secondary endpoints included the development of severe sepsis during the ICU stay, ICU and hospital length of stay and the duration of mechanical ventilation. Propensity score was used to adjust for clinically and statistically relevant variables. Of the 763 patients, 154 patients (20 %) received aspirin. Aspirin therapy was not associated with a reduction in ICU mortality (adjusted OR 1.18, 95 % CI 0.69–2.02, P = 0.55) nor with hospital mortality (adjusted OR 0.95, 95 % CI 0.61–1.50, P = 0.82). Aspirin use had no preferential association with mortality among any of the study subgroups. Additionally, aspirin therapy was associated with higher risk of ICU-acquired severe sepsis, and increased mechanical ventilation duration and ICU length of stay. Our study showed that the use of aspirin in critically ill patients was not associated with lower mortality, but rather with an increased morbidity. ISRCTN07413772 and ISRCTN96294863 ." @default.
• W4254787592 created "2022-05-12" @default.
• W4254787592 creator A5005196213 @default.
• W4254787592 creator A5017442221 @default.
• W4254787592 creator A5045066803 @default.
• W4254787592 creator A5074380996 @default.
• W4254787592 creator A5080894337 @default.
• W4254787592 date "2016-02-05" @default.
• W4254787592 modified "2023-10-16" @default.
• W4254787592 title "Association between aspirin therapy and the outcome in critically ill patients: a nested cohort study" @default.
• W4254787592 cites W107208780 @default.
• W4254787592 cites W1558367558 @default.
• W4254787592 cites W1564536691 @default.
• W4254787592 cites W1600560134 @default.
• W4254787592 cites W179406719 @default.
• W4254787592 cites W1963591185 @default.
• W4254787592 cites W1967906263 @default.
• W4254787592 cites W1974873560 @default.
• W4254787592 cites W1983506403 @default.
• W4254787592 cites W1985187618 @default.
• W4254787592 cites W1986282241 @default.
• W4254787592 cites W1993220550 @default.
• W4254787592 cites W1997241030 @default.
• W4254787592 cites W2001798594 @default.
• W4254787592 cites W2005369178 @default.
• W4254787592 cites W2009818830 @default.
• W4254787592 cites W2011945070 @default.
• W4254787592 cites W2014160424 @default.
• W4254787592 cites W2015038971 @default.
• W4254787592 cites W2019797779 @default.
• W4254787592 cites W2020592012 @default.
• W4254787592 cites W2028579339 @default.
• W4254787592 cites W2036774292 @default.
• W4254787592 cites W2048027358 @default.
• W4254787592 cites W2058406121 @default.
• W4254787592 cites W2059898242 @default.
• W4254787592 cites W2059954832 @default.
• W4254787592 cites W2059981300 @default.
• W4254787592 cites W2061289359 @default.
• W4254787592 cites W2065387895 @default.
• W4254787592 cites W2071637551 @default.
• W4254787592 cites W2073171736 @default.
• W4254787592 cites W2087021723 @default.
• W4254787592 cites W2090622665 @default.
• W4254787592 cites W2107452866 @default.
• W4254787592 cites W2114937634 @default.
• W4254787592 cites W2120386620 @default.
• W4254787592 cites W2121897834 @default.
• W4254787592 cites W2127604161 @default.
• W4254787592 cites W2136735792 @default.
• W4254787592 cites W2141364123 @default.
• W4254787592 cites W2152623360 @default.
• W4254787592 cites W2153875779 @default.
• W4254787592 cites W2154736634 @default.
• W4254787592 cites W2157613247 @default.
• W4254787592 cites W2316376271 @default.
• W4254787592 cites W4234772783 @default.
• W4254787592 cites W4293242440 @default.
• W4254787592 doi "https://doi.org/10.1186/s40360-016-0047-z" @default.
• W4254787592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26850706" @default.
• W4254787592 hasPublicationYear "2016" @default.
• W4254787592 type Work @default.
• W4254787592 citedByCount "28" @default.
• W4254787592 countsByYear W42547875922016 @default.
• W4254787592 countsByYear W42547875922017 @default.
• W4254787592 countsByYear W42547875922018 @default.
• W4254787592 countsByYear W42547875922019 @default.
• W4254787592 countsByYear W42547875922020 @default.
• W4254787592 countsByYear W42547875922021 @default.
• W4254787592 countsByYear W42547875922022 @default.
• W4254787592 countsByYear W42547875922023 @default.
• W4254787592 crossrefType "journal-article" @default.
• W4254787592 hasAuthorship W4254787592A5005196213 @default.
• W4254787592 hasAuthorship W4254787592A5017442221 @default.
• W4254787592 hasAuthorship W4254787592A5045066803 @default.
• W4254787592 hasAuthorship W4254787592A5074380996 @default.
• W4254787592 hasAuthorship W4254787592A5080894337 @default.
• W4254787592 hasBestOaLocation W42547875921 @default.
• W4254787592 hasConcept C126322002 @default.
• W4254787592 hasConcept C168563851 @default.
• W4254787592 hasConcept C177713679 @default.
• W4254787592 hasConcept C17923572 @default.
• W4254787592 hasConcept C179755657 @default.
• W4254787592 hasConcept C201903717 @default.
• W4254787592 hasConcept C203092338 @default.
• W4254787592 hasConcept C2776376669 @default.
• W4254787592 hasConcept C2777080012 @default.
• W4254787592 hasConcept C2777628954 @default.
• W4254787592 hasConcept C2778384902 @default.
• W4254787592 hasConcept C71924100 @default.
• W4254787592 hasConcept C72563966 @default.
• W4254787592 hasConceptScore W4254787592C126322002 @default.
• W4254787592 hasConceptScore W4254787592C168563851 @default.
• W4254787592 hasConceptScore W4254787592C177713679 @default.
• W4254787592 hasConceptScore W4254787592C17923572 @default.
• W4254787592 hasConceptScore W4254787592C179755657 @default.
• W4254787592 hasConceptScore W4254787592C201903717 @default.
• W4254787592 hasConceptScore W4254787592C203092338 @default.
• W4254787592 hasConceptScore W4254787592C2776376669 @default.
• W4254787592 hasConceptScore W4254787592C2777080012 @default.

• next