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- W4254807599 abstract "Abstract The vagus nerve supports diverse autonomic functions and behaviors important for health and survival. To understand how specific components of the vagus contribute to behaviors and long-term physiological effects, it is critical to modulate their activity with anatomical specificity in awake, freely behaving conditions using reliable methods. Here, we introduce an organ-specific scalable, multimodal, wireless optoelectronic device for precise and chronic optogenetic manipulations in vivo. When combined with an advanced, coil-antenna system and a multiplexing strategy for powering 8 individual homecages using a single RF transmitter, the proposed wireless telemetry enables low cost, high-throughput, and precise functional mapping of peripheral neural circuits, including long-term behavioral and physiological measurements. Deployment of these technologies revealed an unexpected role for stomach, non-stretch vagal sensory fibers in suppressing appetite and demonstrated the durability of the miniature wireless device inside harsh gastric conditions." @default.
- W4254807599 created "2022-05-12" @default.
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- W4254807599 date "2020-07-15" @default.
- W4254807599 modified "2023-10-16" @default.
- W4254807599 title "Organ-specific, multimodal, wireless optoelectronics for high-throughput phenotyping of peripheral neural pathways" @default.
- W4254807599 doi "https://doi.org/10.21203/rs.3.rs-38538/v1" @default.
- W4254807599 hasPublicationYear "2020" @default.
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