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- W4254996553 abstract "Background The co-localization analysis of fluorescence microscopy images is a widely used tech- nique in biological research. It is often used to determine the co-distribution of two proteins inside the cell, suggesting that these two proteins could be functionally or physically associated. The limiting step in conducting microscopy image analysis in a graphical interface tool is the selection of the regions of interest for the co-localization of two proteins. Implementation This package provides a simple straight forward workflow for loading fluorescence images, choosing regions of interest and calculating co-localization statistics. Included in the package is a shiny app that can be invoked locally to select the regions of interest where two proteins are interactively co-localized. Availability colocr is available on the comprehensive R archive network, and the source code is available on GitHub as part of the ROpenSci collection, https://github.com/ropensci/colocr . Keywords: R package, co-localization, image-analysis, fluorescence microscopy, statistics" @default.
- W4254996553 created "2022-05-12" @default.
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- W4254996553 date "2019-03-22" @default.
- W4254996553 modified "2023-09-28" @default.
- W4254996553 title "colocr: An R package for conducting co-localization analysis on fluorescence microscopy images" @default.
- W4254996553 doi "https://doi.org/10.7287/peerj.preprints.27613v1" @default.
- W4254996553 hasPublicationYear "2019" @default.
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