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- W4255255271 abstract "633 Thirty-nine pts. had HeartMate LVADs implanted between 12/94 and 10/97 at a single large medical center. Thirty-six males and 3 females with a median age of 56 years had 40 devices implanted (33 pneumatic, 7 vented electric) as a bridge to transplantation. Seventeen of 39 (43.5%) developed LVAD-related infections, including infections of the bloodstream, device pocket, and/or driveline exit site. Infected pts. had a median duration of support of 60 days (range 20-270 days) compared with 46 days (range 4-130 days) in the uninfected pts. Four pts. had prolonged bacteremia prior to implantation, 3 due to septic thrombophlebitis and 1 due to line-related infection. Infected pts. were treated with appropriate antimicrobial therapy and 17 pts. underwent successful transplantation. Twelve (71%) devices were cultured at explantation; 4 grew a pathogen previously identified in multiple blood cultures. Only 1 pt. relapsed following transplantation. Fourteen of 17 infected pts. are presently alive. TableOur experience is that while LVAD-related infections are common, with appropriate (often prolonged) antimicrobial therapy, device-related infections may be suppressed and transplantation performed successfully." @default.
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- W4255255271 date "1998-06-01" @default.
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- W4255255271 title "Four Year Series of Patients with LVAD-Related Infections: Clinical and Microbiologic Experience with Cardiac Transplantation" @default.
- W4255255271 doi "https://doi.org/10.1097/00007890-199806270-00652" @default.
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