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- W4255308935 abstract "Data on clustering and switching during semantic fluency (SF) in patients with first-episode psychosis (PwFEP) are scant. We aimed to investigate (1) clustering and switching on SF in PwFEP using more detailed clustering analyses and (2) the possibility of disproportionate clustering deficits across different SF tasks in PwFEP and healthy subjects (HS), with the latter being suggested by the current literature on patients with schizophrenia. We recruited 22 Croatian-speaking PwFEP with schizophrenia features or symptoms and 22 HS matched in age, sex distribution, and handedness. All patients were medicated and had a mean illness duration of 1 month. The categories animals, trees, vegetables, fruits, and musical instruments were administered for SF. PwFEP produced significantly fewer correct words in the aggregate score, as well as across all categories. The switching rate was significantly higher in PwFEP, but no post hoc comparisons were significant. PwFEP also produced significantly smaller clusters, yet the post hoc comparisons for the tree and fruit task were not significant. A higher switching rate and smaller clusters indicate less efficient functional connectivity within subcategories of the given categories, but not necessarily between the subcategories. Although both less likely to produce a cluster once a switch has been uttered and less likely to produce clusters larger than two words compared to HS, the latter deficit was more pronounced. Our results further suggest that PwFEP might show normal clustering performance on some SF tasks. We discuss the results in the context of the hypothesis of semantic hyperactivation in psychoses." @default.
- W4255308935 created "2022-05-12" @default.
- W4255308935 creator A5026050995 @default.
- W4255308935 creator A5075925914 @default.
- W4255308935 date "2020-10-18" @default.
- W4255308935 modified "2023-09-24" @default.
- W4255308935 title "Semantic fluency reveals reduced functional connectivity between subcategorical co-hyponyms in recent-onset inpatients with first-episode psychosis" @default.
- W4255308935 doi "https://doi.org/10.31234/osf.io/75htx" @default.
- W4255308935 hasPublicationYear "2020" @default.
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