Matches in SemOpenAlex for { <https://semopenalex.org/work/W4255341036> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W4255341036 endingPage "2770" @default.
- W4255341036 startingPage "2766" @default.
- W4255341036 abstract "There is a wide normal range of coagulation factor XIII activity that has never been adequately explained. A polymorphism substituting leucine for valine at position 34 in the activation peptide of the A subunit of factor XIII has recently been discovered in nondeficient individuals, and the present studies indicate that the leucine substitution results in a significant increase in transglutaminase activity. The frequency of the Leu34 allele in the Australian Caucasian population is 0.27, which is high enough to suggest that the inheritance of either the Val34 or Leu34 alleles may contribute to the wide normal range of activity. Although there has been structural evidence indicating that the activation peptide does not dissociate from the enzyme after thrombin cleavage, the discovery of elevated activity resulting from the Leu34 substitution is the first direct evidence that the activation peptide plays a continuing role in the function of factor XIII. © 1998 by The American Society of Hematology." @default.
- W4255341036 created "2022-05-12" @default.
- W4255341036 creator A5014130762 @default.
- W4255341036 creator A5071229773 @default.
- W4255341036 date "1998-10-15" @default.
- W4255341036 modified "2023-09-27" @default.
- W4255341036 title "The Val34Leu Polymorphism in the A Subunit of Coagulation Factor XIII Contributes to the Large Normal Range in Activity and Demonstrates That the Activation Peptide Plays a Role in Catalytic Activity" @default.
- W4255341036 cites W1067939983 @default.
- W4255341036 cites W1531281563 @default.
- W4255341036 cites W1538720735 @default.
- W4255341036 cites W1544756659 @default.
- W4255341036 cites W1775749144 @default.
- W4255341036 cites W1987051801 @default.
- W4255341036 cites W1987708536 @default.
- W4255341036 cites W1991161452 @default.
- W4255341036 cites W2002813720 @default.
- W4255341036 cites W2008859628 @default.
- W4255341036 cites W2019875341 @default.
- W4255341036 cites W2021504472 @default.
- W4255341036 cites W2043142931 @default.
- W4255341036 cites W2065084878 @default.
- W4255341036 cites W2065421971 @default.
- W4255341036 cites W2086541369 @default.
- W4255341036 cites W2106812532 @default.
- W4255341036 cites W2167803193 @default.
- W4255341036 cites W2233311865 @default.
- W4255341036 cites W2434186044 @default.
- W4255341036 cites W32567474 @default.
- W4255341036 cites W33124927 @default.
- W4255341036 cites W4239660168 @default.
- W4255341036 cites W4240065971 @default.
- W4255341036 doi "https://doi.org/10.1182/blood.v92.8.2766.420k26_2766_2770" @default.
- W4255341036 hasPublicationYear "1998" @default.
- W4255341036 type Work @default.
- W4255341036 citedByCount "1" @default.
- W4255341036 crossrefType "journal-article" @default.
- W4255341036 hasAuthorship W4255341036A5014130762 @default.
- W4255341036 hasAuthorship W4255341036A5071229773 @default.
- W4255341036 hasConcept C104292427 @default.
- W4255341036 hasConcept C104317684 @default.
- W4255341036 hasConcept C178498320 @default.
- W4255341036 hasConcept C180754005 @default.
- W4255341036 hasConcept C181199279 @default.
- W4255341036 hasConcept C185592680 @default.
- W4255341036 hasConcept C2777573094 @default.
- W4255341036 hasConcept C2779036427 @default.
- W4255341036 hasConcept C2779281246 @default.
- W4255341036 hasConcept C2779672106 @default.
- W4255341036 hasConcept C2908647359 @default.
- W4255341036 hasConcept C515207424 @default.
- W4255341036 hasConcept C54355233 @default.
- W4255341036 hasConcept C55493867 @default.
- W4255341036 hasConcept C71924100 @default.
- W4255341036 hasConcept C86803240 @default.
- W4255341036 hasConcept C99454951 @default.
- W4255341036 hasConceptScore W4255341036C104292427 @default.
- W4255341036 hasConceptScore W4255341036C104317684 @default.
- W4255341036 hasConceptScore W4255341036C178498320 @default.
- W4255341036 hasConceptScore W4255341036C180754005 @default.
- W4255341036 hasConceptScore W4255341036C181199279 @default.
- W4255341036 hasConceptScore W4255341036C185592680 @default.
- W4255341036 hasConceptScore W4255341036C2777573094 @default.
- W4255341036 hasConceptScore W4255341036C2779036427 @default.
- W4255341036 hasConceptScore W4255341036C2779281246 @default.
- W4255341036 hasConceptScore W4255341036C2779672106 @default.
- W4255341036 hasConceptScore W4255341036C2908647359 @default.
- W4255341036 hasConceptScore W4255341036C515207424 @default.
- W4255341036 hasConceptScore W4255341036C54355233 @default.
- W4255341036 hasConceptScore W4255341036C55493867 @default.
- W4255341036 hasConceptScore W4255341036C71924100 @default.
- W4255341036 hasConceptScore W4255341036C86803240 @default.
- W4255341036 hasConceptScore W4255341036C99454951 @default.
- W4255341036 hasIssue "8" @default.
- W4255341036 hasLocation W42553410361 @default.
- W4255341036 hasOpenAccess W4255341036 @default.
- W4255341036 hasPrimaryLocation W42553410361 @default.
- W4255341036 hasRelatedWork W13313469 @default.
- W4255341036 hasRelatedWork W1637687 @default.
- W4255341036 hasRelatedWork W17269619 @default.
- W4255341036 hasRelatedWork W20005358 @default.
- W4255341036 hasRelatedWork W21525851 @default.
- W4255341036 hasRelatedWork W22335531 @default.
- W4255341036 hasRelatedWork W22403897 @default.
- W4255341036 hasRelatedWork W4939852 @default.
- W4255341036 hasRelatedWork W7790069 @default.
- W4255341036 hasRelatedWork W9340601 @default.
- W4255341036 hasVolume "92" @default.
- W4255341036 isParatext "false" @default.
- W4255341036 isRetracted "false" @default.
- W4255341036 workType "article" @default.