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- W4255389623 abstract "Functional domains of the 50 kDa (427 amino acid residues) of the human 1,25-dihydroxyvitamin D3 receptor necessary for stimulation of osteocalcin gene transcription were mapped. Amino acid residues 1-144 comprise the DNA-binding domain, while the C-terminal 114 residues define the 1,25(OH)2D3 ligand binding domain. In the 5'-promoter region of the human osteocalcin gene, a specific 21-base-pair DNA element (-489 to -509) was identified as the specific site of binding of the DNA-binding domain of the 1,25(OH)2D3 receptor." @default.
- W4255389623 created "2022-05-12" @default.
- W4255389623 date "2009-04-27" @default.
- W4255389623 modified "2023-09-30" @default.
- W4255389623 title "IDENTIFICATION OF FUNCTIONAL DOMAINS ON THE 1,25-DIHYDROXYVITAMIN-D3 RECEPTOR" @default.
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- W4255389623 doi "https://doi.org/10.1111/j.1753-4887.1990.tb02931.x" @default.
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- W4255389623 hasPublicationYear "2009" @default.
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