Matches in SemOpenAlex for { <https://semopenalex.org/work/W4255439077> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W4255439077 endingPage "4" @default.
- W4255439077 startingPage "1" @default.
- W4255439077 abstract "Laropiprant is a selective antagonist of prostaglandin D2 receptor 1. It is mainly used for the treatment of niacin‐induced flushing. Rapid absorption of the administered laropiprant was observed in six healthy male subjects after a single oral dose of [ 14 C‐methylsulfonyl]‐laropiprant. The unchanged [ 14 C]‐laropiprant represented 30% of the radioactivity in plasma. The acyl glucuronide conjugate of laropiprant was the only other radiochemical component in plasma. The major route of excretion of radioactivity was via feces (68% of the administered dose). Urinary excretion averaged 22% of the administered dose. The acyl glucuronide conjugate was the major excreted metabolite. Minor metabolites included hydroxylation products and their further keto oxidation product, and glucuronide conjugates of them." @default.
- W4255439077 created "2022-05-12" @default.
- W4255439077 creator A5042212196 @default.
- W4255439077 date "2013-10-13" @default.
- W4255439077 modified "2023-09-26" @default.
- W4255439077 title "Laropiprant" @default.
- W4255439077 cites W2127911111 @default.
- W4255439077 cites W2135758343 @default.
- W4255439077 cites W2148798174 @default.
- W4255439077 doi "https://doi.org/10.1002/9781118541203.xen196" @default.
- W4255439077 hasPublicationYear "2013" @default.
- W4255439077 type Work @default.
- W4255439077 citedByCount "0" @default.
- W4255439077 crossrefType "other" @default.
- W4255439077 hasAuthorship W4255439077A5042212196 @default.
- W4255439077 hasConcept C10146269 @default.
- W4255439077 hasConcept C112705442 @default.
- W4255439077 hasConcept C134306372 @default.
- W4255439077 hasConcept C181199279 @default.
- W4255439077 hasConcept C185592680 @default.
- W4255439077 hasConcept C197336794 @default.
- W4255439077 hasConcept C2777477808 @default.
- W4255439077 hasConcept C2779186261 @default.
- W4255439077 hasConcept C2780026642 @default.
- W4255439077 hasConcept C2780092750 @default.
- W4255439077 hasConcept C2781109383 @default.
- W4255439077 hasConcept C33923547 @default.
- W4255439077 hasConcept C55493867 @default.
- W4255439077 hasConcept C71924100 @default.
- W4255439077 hasConcept C98274493 @default.
- W4255439077 hasConceptScore W4255439077C10146269 @default.
- W4255439077 hasConceptScore W4255439077C112705442 @default.
- W4255439077 hasConceptScore W4255439077C134306372 @default.
- W4255439077 hasConceptScore W4255439077C181199279 @default.
- W4255439077 hasConceptScore W4255439077C185592680 @default.
- W4255439077 hasConceptScore W4255439077C197336794 @default.
- W4255439077 hasConceptScore W4255439077C2777477808 @default.
- W4255439077 hasConceptScore W4255439077C2779186261 @default.
- W4255439077 hasConceptScore W4255439077C2780026642 @default.
- W4255439077 hasConceptScore W4255439077C2780092750 @default.
- W4255439077 hasConceptScore W4255439077C2781109383 @default.
- W4255439077 hasConceptScore W4255439077C33923547 @default.
- W4255439077 hasConceptScore W4255439077C55493867 @default.
- W4255439077 hasConceptScore W4255439077C71924100 @default.
- W4255439077 hasConceptScore W4255439077C98274493 @default.
- W4255439077 hasLocation W42554390771 @default.
- W4255439077 hasOpenAccess W4255439077 @default.
- W4255439077 hasPrimaryLocation W42554390771 @default.
- W4255439077 hasRelatedWork W1021316407 @default.
- W4255439077 hasRelatedWork W2059443350 @default.
- W4255439077 hasRelatedWork W2067685349 @default.
- W4255439077 hasRelatedWork W2081993762 @default.
- W4255439077 hasRelatedWork W2292927004 @default.
- W4255439077 hasRelatedWork W2406801323 @default.
- W4255439077 hasRelatedWork W2430409124 @default.
- W4255439077 hasRelatedWork W2739952925 @default.
- W4255439077 hasRelatedWork W4230664429 @default.
- W4255439077 hasRelatedWork W2485882805 @default.
- W4255439077 isParatext "false" @default.
- W4255439077 isRetracted "false" @default.
- W4255439077 workType "other" @default.