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- W4255538905 abstract "The regional anatomy around the DBS lead in the subthalamic nucleus (STN) determines efficacy and adverse effects. Understanding the regional anatomy allows the programmer to adjust the stimulation to provide optimal benefit and the absence of adverse effects.The STN lies near the junction of the diencephalon and mesencephalon. It is just ventral to the thalamus, just lateral to the brachium conjunctivum and red nucleus, and medial and dorsal to the internal capsule. These structures are important because inappropriate stimulation causes side effects. For examples: Electrical fields spreading to ascending sensory medial lemniscus and spinothalamic pathways behind the STN produce paresthesias. Inadvertent stimulation of the brachium conjunctivum can cause ataxia and loss of balance. The red nucleus lies in the brachium conjunctivum, and the exiting axons from the oculomotor nucleus run within the red nucleus. Electrical fields spreading to these structures can result in disconjugate gaze and diplopia. Stimulating the internal capsule laterally or dorsally can cause tonic muscle contractions." @default.
- W4255538905 created "2022-05-12" @default.
- W4255538905 creator A5064258741 @default.
- W4255538905 date "2016-11-01" @default.
- W4255538905 modified "2023-09-25" @default.
- W4255538905 title "Approach to DBS in the Vicinity of the Subthalamic Nucleus" @default.
- W4255538905 doi "https://doi.org/10.1093/med/9780190259600.003.0011" @default.
- W4255538905 hasPublicationYear "2016" @default.
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