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• W4255656321 abstract "Abstract Background Incisional hernia (IH), especially giant incisional hernia negatively affects a patient’s quality of life. Previous literatures often used muscle area measured by CT to assess loss of muscle mass and to estimate its relationship with diseases. For now, a few literatures have discussed potential effect of psoas muscle area on IH, while very limited attention has been paid to the association between psoas fatty infiltration and incidence of IH. In this study, we aimed to investigate if psoas CT measurement parameters, including average CT attenuation, fatty infiltration rate and psoas muscle index, were associated with IH. Methods Adult patients (> 18 years old) who had a history of appendicectomy and underwent CT examination in Beijing Chaoyang hospital from January 2018 to December 2019 were enrolled. All patients were classified into IH group and non-IH group. Psoas CT attenuation, fatty infiltration rate (FIR) and psoas muscle index (PMI) were measured or calculated. Sarcopenia was defined according to PMI. Differences in indices between the two groups were compared. Logistic regression model was applied to assess the effects of psoas CT measurement parameters on the occurrence of IH. Results 120 consecutive patients were included in this study. Psoas CT attenuation ( p = 0.031) and PMI ( p = 0.042) in IH group were significantly lower than those in non-IH group, and FIR in IH group was significantly higher than that in non-IH group ( p < 0.001). Psoas CT attenuation, FIR, PMI, age, gender and smoking were significant factors in univariate logistic regression analysis. After adjusting for confounding factors, multivariate logistic regression analysis demonstrated that psoas CT attenuation was an independent protective factor ( p = 0.042), and FIR an independent risk factor ( p = 0.018); while PMI ( p = 0.118) and sarcopenia ( p = 0.663) showed no significant effect on incidence of IH. Conclusion Decreased CT attenuation and increased FIR of psoas are risk factors for IH after appendectomy." @default.
• W4255656321 created "2022-05-12" @default.
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• W4255656321 date "2020-10-29" @default.
• W4255656321 modified "2023-10-18" @default.
• W4255656321 title "Psoas CT Attenuation and Fatty Infiltration Rate Predict Incisional Hernia After Appendicectomy" @default.
• W4255656321 doi "https://doi.org/10.21203/rs.3.rs-97662/v1" @default.
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