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- W4256003522 abstract "Abstract Ein polymeres Therapeutikum für die kombinierte Antikrebs‐ und antiangiogenetische Therapie inhibiert die Proliferation von Prostatakarzinomzellen sowie die Proliferation, Migration und Röhrenbildung von Endothelzellen. Das Nanokonjugat besteht aus einem N ‐(2‐Hydroxypropyl)methacrylamid(HPMA)‐Copolymer, dem Bisphosphonat Alendronat (zur Ansteuerung von Knochengewebe) und dem Chemotherapeutikum Paclitaxel (PTX), das durch Cathepsin B abgespalten wird (siehe Schema). magnified image" @default.
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- W4256003522 date "2009-03-30" @default.
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- W4256003522 title "Targeting Bone Metastases with a Bispecific Anticancer and Antiangiogenic Polymer-Alendronate-Taxane Conjugate" @default.
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