Matches in SemOpenAlex for { <https://semopenalex.org/work/W4256039750> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4256039750 abstract "Abstract Background : The emergence of carbapenem-resistant Enterobacteriaceae made the treatment difficult, which has become a major issue of public health. A sharp increase of carbapenem-resistance rate in Klebsiella pneumoniae was observed in a maternity and child health care hospital in Zunyi, China, in 2014.To investigate the cause and epidemiology of the carbapenem-resistant Klebsiella pneumoniae (CRKp) in the affected hospital. Methods : In 2015-2016, CRKp isolated from all the clinical samples were analyzed to identify the carbapenem-resistance genes. They were then fingerprinted in order to determine their genetic relationship. Clinical data such as usage of imipenem in 2012-2016 and the nosocomial infection surveillance data were analyzed Results : Thirty five isolates of CRKp out of 4328 various pathogens were obtained and bla NDM-1 was identified to be the most common resistant gene present in the CRKp isolates. The fingerprint analysis identified 15 major clusters of CRKp isolates. The bacteria with close proximity relationship tended to be from the same wards. However, a few CRKp isolates from different wards were found to be genetically highly related. The clinical data showed a significantly higher usage of carbapenems in 2012-2013, before the CRKp rate sharply increased in 2014. The nosocomial infection surveillance showed unexpected high rate of failures to meet the requirement of the hospital environment hygiene and hand hygiene in the neonatal ward. Conclusion : The increasing isolation rate of CRKp was associated with poorly regulated usage of carbapenems, impropriate medical practices and the poor hospital environmental hygiene and hand hygiene." @default.
- W4256039750 created "2022-05-12" @default.
- W4256039750 creator A5019891778 @default.
- W4256039750 creator A5022179714 @default.
- W4256039750 creator A5057117256 @default.
- W4256039750 creator A5064721095 @default.
- W4256039750 creator A5084867393 @default.
- W4256039750 creator A5090079801 @default.
- W4256039750 date "2020-06-08" @default.
- W4256039750 modified "2023-09-27" @default.
- W4256039750 title "A possible link between improper use of carbapenems and prevalence of carbapenem-resistant Klebsiella Pneumoniae in a hospital" @default.
- W4256039750 doi "https://doi.org/10.21203/rs.3.rs-33310/v1" @default.
- W4256039750 hasPublicationYear "2020" @default.
- W4256039750 type Work @default.
- W4256039750 citedByCount "0" @default.
- W4256039750 crossrefType "posted-content" @default.
- W4256039750 hasAuthorship W4256039750A5019891778 @default.
- W4256039750 hasAuthorship W4256039750A5022179714 @default.
- W4256039750 hasAuthorship W4256039750A5057117256 @default.
- W4256039750 hasAuthorship W4256039750A5064721095 @default.
- W4256039750 hasAuthorship W4256039750A5084867393 @default.
- W4256039750 hasAuthorship W4256039750A5090079801 @default.
- W4256039750 hasBestOaLocation W42560397501 @default.
- W4256039750 hasConcept C104317684 @default.
- W4256039750 hasConcept C107130276 @default.
- W4256039750 hasConcept C126322002 @default.
- W4256039750 hasConcept C142724271 @default.
- W4256039750 hasConcept C2775992322 @default.
- W4256039750 hasConcept C2776685102 @default.
- W4256039750 hasConcept C2777058267 @default.
- W4256039750 hasConcept C2779116282 @default.
- W4256039750 hasConcept C2779631663 @default.
- W4256039750 hasConcept C501593827 @default.
- W4256039750 hasConcept C54355233 @default.
- W4256039750 hasConcept C547475151 @default.
- W4256039750 hasConcept C547646559 @default.
- W4256039750 hasConcept C71924100 @default.
- W4256039750 hasConcept C86803240 @default.
- W4256039750 hasConcept C89423630 @default.
- W4256039750 hasConcept C94665300 @default.
- W4256039750 hasConceptScore W4256039750C104317684 @default.
- W4256039750 hasConceptScore W4256039750C107130276 @default.
- W4256039750 hasConceptScore W4256039750C126322002 @default.
- W4256039750 hasConceptScore W4256039750C142724271 @default.
- W4256039750 hasConceptScore W4256039750C2775992322 @default.
- W4256039750 hasConceptScore W4256039750C2776685102 @default.
- W4256039750 hasConceptScore W4256039750C2777058267 @default.
- W4256039750 hasConceptScore W4256039750C2779116282 @default.
- W4256039750 hasConceptScore W4256039750C2779631663 @default.
- W4256039750 hasConceptScore W4256039750C501593827 @default.
- W4256039750 hasConceptScore W4256039750C54355233 @default.
- W4256039750 hasConceptScore W4256039750C547475151 @default.
- W4256039750 hasConceptScore W4256039750C547646559 @default.
- W4256039750 hasConceptScore W4256039750C71924100 @default.
- W4256039750 hasConceptScore W4256039750C86803240 @default.
- W4256039750 hasConceptScore W4256039750C89423630 @default.
- W4256039750 hasConceptScore W4256039750C94665300 @default.
- W4256039750 hasLocation W42560397501 @default.
- W4256039750 hasOpenAccess W4256039750 @default.
- W4256039750 hasPrimaryLocation W42560397501 @default.
- W4256039750 hasRelatedWork W13087184 @default.
- W4256039750 hasRelatedWork W13584953 @default.
- W4256039750 hasRelatedWork W14370425 @default.
- W4256039750 hasRelatedWork W16121240 @default.
- W4256039750 hasRelatedWork W19807120 @default.
- W4256039750 hasRelatedWork W20034410 @default.
- W4256039750 hasRelatedWork W20565358 @default.
- W4256039750 hasRelatedWork W4856142 @default.
- W4256039750 hasRelatedWork W5477811 @default.
- W4256039750 hasRelatedWork W17054758 @default.
- W4256039750 isParatext "false" @default.
- W4256039750 isRetracted "false" @default.
- W4256039750 workType "article" @default.