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• W4256130009 endingPage "79" @default.
• W4256130009 startingPage "63" @default.
• W4256130009 abstract "Mild traumatic brain injury (mTBI) is a condition of normal neuroimaging, because conventional MRI is not sensitive to brain lesions. Neurocognitive deficits persist for years after injury in 15% of patients. Persistent TAI can continue after the trauma and contribute to progressive disability. Neuropathologic studies underestimate the total axonal damage, by failure to identify fine-caliber unmyelinated fiber. Swollen axons represent the “tip of the iceberg” of damage. Progression of molecular changes, including mitochondrial dysfunction, leads to secondary injuries. Primary low-intensity “invisible injury” is solely detectable at ultrastructural levels. Over the long term, mTBI is not a static event but a progressive injury, increasing risk of neurodegenerative diseases. Lack of evidence of brain injury has led to the development of more sensitive methods: morphometric MRI (VBM, DTI) and functional techniques (fMRI, PET, SPECT). By deformation of the surface of gray matter cingulate gyrus and disruption of long-coursing WM of CB structures, striking the falx, mTBI causes alteration of cingulate functions. Postconcussion, blast, and whiplash-associated disorders are the main mechanisms providing behavior and cognitive symptoms after mTBI." @default.
• W4256130009 created "2022-05-12" @default.
• W4256130009 creator A5007047129 @default.
• W4256130009 creator A5056247087 @default.
• W4256130009 date "2010-04-01" @default.
• W4256130009 modified "2023-09-24" @default.
• W4256130009 title "Imaging of Head Trauma" @default.
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• W4256130009 doi "https://doi.org/10.1053/j.ro.2009.09.007" @default.
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