Matches in SemOpenAlex for { <https://semopenalex.org/work/W4256142746> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W4256142746 endingPage "16" @default.
- W4256142746 startingPage "13" @default.
- W4256142746 abstract "The effect of aconitine, a plant alkaloid known to bind at site 2 of the sodium channel, was investigated on neuronal excitability in hippocampal slices of adult and juvenile rats. Aconitine (0.01–1 μM) diminished the extracellularly recorded population spike in a concentration-dependent manner. At each concentration, the inhibitory action of aconitine was significantly stronger and was obtained after a shorter latency in slices of juvenile rats (20–25 days) as compared with slices of adult rats (45–50 days). When maximal inhibition was achieved, a prolonged application of aconitine evoked an increase in spike amplitude of up to 15% in slices of juvenile but not of adult rats. The latency of recovery from the aconitine-induced inhibition was also significantly shorter in slices of juvenile rats. This effect was concentration-dependent and significantly stronger in slices of juvenile rats. These observations indicate that juvenile hippocampi have a higher susceptibility to the effect of aconitine, but also provide a partial protective mechanism." @default.
- W4256142746 created "2022-05-12" @default.
- W4256142746 creator A5081728572 @default.
- W4256142746 date "1996-09-20" @default.
- W4256142746 modified "2023-09-26" @default.
- W4256142746 title "Age-dependent differences in sensitivity to aconitine of rat hippocampal slices" @default.
- W4256142746 doi "https://doi.org/10.1016/s0304-3940(96)12989-x" @default.
- W4256142746 hasPublicationYear "1996" @default.
- W4256142746 type Work @default.
- W4256142746 citedByCount "0" @default.
- W4256142746 crossrefType "journal-article" @default.
- W4256142746 hasAuthorship W4256142746A5081728572 @default.
- W4256142746 hasConcept C115961737 @default.
- W4256142746 hasConcept C126322002 @default.
- W4256142746 hasConcept C134018914 @default.
- W4256142746 hasConcept C148762608 @default.
- W4256142746 hasConcept C17077164 @default.
- W4256142746 hasConcept C178790620 @default.
- W4256142746 hasConcept C185592680 @default.
- W4256142746 hasConcept C2776464000 @default.
- W4256142746 hasConcept C2777547430 @default.
- W4256142746 hasConcept C2777667214 @default.
- W4256142746 hasConcept C2779277159 @default.
- W4256142746 hasConcept C2908647359 @default.
- W4256142746 hasConcept C42219234 @default.
- W4256142746 hasConcept C50952357 @default.
- W4256142746 hasConcept C537181965 @default.
- W4256142746 hasConcept C54355233 @default.
- W4256142746 hasConcept C71240020 @default.
- W4256142746 hasConcept C71924100 @default.
- W4256142746 hasConcept C86803240 @default.
- W4256142746 hasConcept C98274493 @default.
- W4256142746 hasConcept C99454951 @default.
- W4256142746 hasConceptScore W4256142746C115961737 @default.
- W4256142746 hasConceptScore W4256142746C126322002 @default.
- W4256142746 hasConceptScore W4256142746C134018914 @default.
- W4256142746 hasConceptScore W4256142746C148762608 @default.
- W4256142746 hasConceptScore W4256142746C17077164 @default.
- W4256142746 hasConceptScore W4256142746C178790620 @default.
- W4256142746 hasConceptScore W4256142746C185592680 @default.
- W4256142746 hasConceptScore W4256142746C2776464000 @default.
- W4256142746 hasConceptScore W4256142746C2777547430 @default.
- W4256142746 hasConceptScore W4256142746C2777667214 @default.
- W4256142746 hasConceptScore W4256142746C2779277159 @default.
- W4256142746 hasConceptScore W4256142746C2908647359 @default.
- W4256142746 hasConceptScore W4256142746C42219234 @default.
- W4256142746 hasConceptScore W4256142746C50952357 @default.
- W4256142746 hasConceptScore W4256142746C537181965 @default.
- W4256142746 hasConceptScore W4256142746C54355233 @default.
- W4256142746 hasConceptScore W4256142746C71240020 @default.
- W4256142746 hasConceptScore W4256142746C71924100 @default.
- W4256142746 hasConceptScore W4256142746C86803240 @default.
- W4256142746 hasConceptScore W4256142746C98274493 @default.
- W4256142746 hasConceptScore W4256142746C99454951 @default.
- W4256142746 hasIssue "1" @default.
- W4256142746 hasLocation W42561427461 @default.
- W4256142746 hasOpenAccess W4256142746 @default.
- W4256142746 hasPrimaryLocation W42561427461 @default.
- W4256142746 hasRelatedWork W1968289018 @default.
- W4256142746 hasRelatedWork W1998134099 @default.
- W4256142746 hasRelatedWork W2001793878 @default.
- W4256142746 hasRelatedWork W2005798104 @default.
- W4256142746 hasRelatedWork W2006202112 @default.
- W4256142746 hasRelatedWork W2013228473 @default.
- W4256142746 hasRelatedWork W2059675769 @default.
- W4256142746 hasRelatedWork W2068667786 @default.
- W4256142746 hasRelatedWork W2402585689 @default.
- W4256142746 hasRelatedWork W43263413 @default.
- W4256142746 hasVolume "216" @default.
- W4256142746 isParatext "false" @default.
- W4256142746 isRetracted "false" @default.
- W4256142746 workType "article" @default.