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- W4256189706 abstract "Povidone-iodine and chlorhexidine surgical scrub and skin preparation solutions were assessed by comparing postoperative wound infection rates in a prospective, randomized study of 866 patients. The frequency of wound infection overall, as agreed by two observers, was 14·8 per cent in the povidone-iodine group and 9·7 per cent in the chlorhexidine group (P = 0·03) at the time of patients' discharge from hospital. The difference between the compounds was not significant at a ‘standard’ observation period of three to four days after operation. There were significantly fewer infections with chlorhexidine than with povidone-iodine in operations on the biliary tract and in ‘clean’ non-abdominal operations, but there were more infections (not significantly so) with chlorhexidine than with povidoneiodine in large bowel surgery, other laparotomies and in operations on hernia, genitalia and varicose veins. The differences in bacterial isolates from wounds tended to follow the above patterns. We conclude that, on the evidence of this study, there is no overwhelming case for using one compound rather than the other as an all-purpose preparation and scrub." @default.
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- W4256189706 date "1982-03-01" @default.
- W4256189706 modified "2023-10-18" @default.
- W4256189706 title "A comparison of the use of povidone-iodine and chlorhexidine in the prophylaxis of postoperative wound infection" @default.
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- W4256189706 doi "https://doi.org/10.1016/0195-6701(82)90031-7" @default.
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