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- W4256266644 abstract "A series of 29 derivatives was obtained from the ditetrahydropyranyl ether of coumermycin A1 by treatment with 3- and 3, 5-substituted 4-acetoxy and 4-methoxy benzoyl chlorides. Many of the required acids were hitherto unknown and three were obtained from novobiocin by published procedures. Although all of the semisynthetic coumermycins so obtained were potent antibiotics, they showed significant differences in activity depending on the nature of the substituents in the benzamido portion of the molecules." @default.
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- W4256266644 date "1968-01-01" @default.
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- W4256266644 title "SEMISYNTHETIC COUMERMYCINS. II" @default.
- W4256266644 doi "https://doi.org/10.7164/antibiotics.21.603" @default.
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