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- W4256276992 abstract "Curli are adhesive surface fibers produced by many Enterobacteriaceae, such as Escherichia coli and Salmonella enterica. They are implicated in bacterial attachment and invasion to epithelial cells. In this study, atomic force microscopy was used to determine the effects of curli on topology and mechanical properties of live E. coli cells. Young's moduli of both curli-deficient and curli-overproducing mutants were significantly lower than that of their wild-type strain, while decay lengths of the former strains were higher than that of the latter strain. Surprisingly, topological images showed that, unlike the wild-type and curli-overproducing mutant, the curli-deficient mutant produced a large number of flagella-like fibers, which may explain why the strain had a lower Young's modulus than the wild-type. These results suggest that the mechanical properties of bacterial surfaces are greatly affected by the presence of filamentous structures such as curli and flagella." @default.
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- W4256276992 date "2013-01-01" @default.
- W4256276992 modified "2023-09-30" @default.
- W4256276992 title "Characterization of Curli a Production on Living Bacterial Surfaces by Scanning Probe Microscopy" @default.
- W4256276992 doi "https://doi.org/10.1016/j.bpj.2012.11.2835" @default.
- W4256276992 hasPublicationYear "2013" @default.
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