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- W4256366170 abstract "OBJECTIVE AND IMPORTANCE Diencephalic syndrome of emaciation (DS) is seen almost exclusively in infants and young children, and only two cases of DS in adults have been reported previously. We describe a case of DS associated with a third ventricle intrinsic craniopharyngioma in an adult patient. CLINICAL PRESENTATION A 54-year-old man presented with profound emaciation, disorientation, memory loss, and psychological disorders. Computed tomographic scanning and magnetic resonance imaging of his brain disclosed a tumor within the third ventricle. The preoperative endocrinological examination indicated an elevated growth hormone level and a decreased somatomedin C level. INTERVENTION The patient underwent partial resection of the tumor, which was adherent to the floor of the third ventricle but not to the ventricle wall, by an interhemispheric-transcallosal approach. The histological examination revealed a squamous papillary-type craniopharyngioma. The patient received 50 Gy of radiotherapy, which resulted in 90 to 95% reduction of the tumor size within 6 months, as indicated by the magnetic resonance images presented. The psychological disorders, memory disturbance, and severe emaciation improved gradually thereafter. CONCLUSION Although extremely rare, DS can occur in an adult harboring a tumor in the anterior hypothalamus." @default.
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- W4256366170 date "2003-01-01" @default.
- W4256366170 modified "2023-10-14" @default.
- W4256366170 title "Diencephalic Syndrome of Emaciation in an Adult Associated with a Third Ventricle Intrinsic Craniopharyngioma: Case Report" @default.
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- W4256366170 doi "https://doi.org/10.1227/00006123-200301000-00029" @default.
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