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- W4256552989 abstract "<div>Digital light processing (DLP) is one of the most accurate and fastest additive manufacturing</div><div>technologies to produce a variety of products, from patient-customized biomedical implants to</div><div>consumer goods; however, DLP’s use in tissue engineering is limited largely due to a lack of</div><div>biodegradable resins. Herein, a library of biodegradable urethane acrylate-capped poly(esters)</div><div>(with variations in molecular weight) is investigated as the basis for a DLP printable ink for</div><div>tissue engineering. The synthesized oligomers show good printability in a DLP resin, capable</div><div>of creating complex structures with mechanical properties matching those of medium-soft</div><div>tissues (1–3 MPa). While fabricated films from different molecular weight resins showed few</div><div>differences in surface topology, wettability, and protein adsorption, the adhesion and metabolic</div><div>activity of L929 and human dermal fibroblasts (HDFs) were significantly different: resins from</div><div>higher molecular weight oligomers provided greater cell adhesion and metabolic activity. These</div><div>printable and biodegradable resins show the importance of oligomer molecular weight on</div><div>scaffold properties, and facilitate the printing of elastomeric customizable scaffolds for a variety</div><div>of tissue engineering applications.</div>" @default.
- W4256552989 created "2022-05-12" @default.
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- W4256552989 date "2020-04-01" @default.
- W4256552989 modified "2023-09-27" @default.
- W4256552989 title "Biodegradable Poly(ester) Urethane Acrylate Resins for Digital Light Processing: From Polymer Synthesis to 3D Printed Tissue Engineering Constructs" @default.
- W4256552989 doi "https://doi.org/10.26434/chemrxiv.12053037" @default.
- W4256552989 hasPublicationYear "2020" @default.
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