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- W4256553667 abstract "Abstract Objectives: To compare the laboratory and clinical out-come of patients who received solvent/detergent-treated plasma (SDP) and fresh-frozen plasma (FFP). Methods: A randomized, double-blinded study to assess the ability of SDP and FFP to reduce a prolonged prothrombin time (PT to ≤ 15 s in patients with acquired coagulation deficits. Results: 45 patients (22 SDP vs. 23 FFP) were treated with 71 infusions. There were no significant differences in mean dose of plasma infused (7.8 ml/kg for SDP vs. 8.0 ml/kg for FFP, p = 0.46), percentage of patients who corrected their PT to ≤ 15 s (32% for SDP vs. 26% for FFP, p = 0.67), or percentage of patients whose bleeding ceased (27% for SDP vs. 22% for FFP). Conclusion: No clinical or statistically significant differences were observed after infusion with SDP or FFP in patients with acquired coagulation deficits." @default.
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- W4256553667 date "2000-11-01" @default.
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- W4256553667 title "Evaluation of Solvent/Detergent-Treated Plasma in Patients with a Prolonged Prothrombin Time" @default.
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- W4256553667 doi "https://doi.org/10.1046/j.1423-0410.2000.7930161.x" @default.
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