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- W4256607075 abstract "The development of blood products for the treatment of hemophilia has dramatically altered the prognosis for those patients who have regular access to safe products. In recent years, the relative merits of plasma versus recombinant products have been a major topic of debate. The arguments focus primarily on safety with regard to transmission of pathogens. However, the relative immunogenicity of the two classes of product has also been a subject of controversy. It has also been suggested that plasma-derived products may be more effective than recombinant products in achieving immune tolerance in patients with inhibitors. The cost of recombinant factor VIII concentrates has fallen significantly in recent years and is now similar to that of plasma products. It is clear that there will continue to be a global requirement for plasma-derived as well recombinant coagulation factor concentrates for many years to come." @default.
- W4256607075 created "2022-05-12" @default.
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- W4256607075 date "2014-04-24" @default.
- W4256607075 modified "2023-09-24" @default.
- W4256607075 title "Products Used to Treat Hemophilia: Plasma-derived Coagulation Factor Concentrates" @default.
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- W4256607075 doi "https://doi.org/10.1002/9781118398258.ch24" @default.
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