Matches in SemOpenAlex for { <https://semopenalex.org/work/W4256703886> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4256703886 endingPage "186" @default.
- W4256703886 startingPage "181" @default.
- W4256703886 abstract "Elevated hematocrits, which are found in many high-altitude populations, increase the oxygen-carrying capacity of blood and may represent an adaptation to hypoxic environments. However, as high hematocrit increases blood viscosity, which in turn is associated with hypertension and heart disease, it may be advantageous for high-altitude populations to limit other factors that contribute to increased blood viscosity. One such factor is the plasma concentration of the coagulation protein fibrinogen. Several common polymorphisms in the β-fibrinogen gene have been identified that affect fibrinogen concentrations. We determined the allele frequencies of three of these polymorphisms (G/A-455(HaeIII), C/T-148(HindIII), and G/A+448(MnlI)) in sample groups drawn from three populations: Quechua-speaking natives living at over 3,200 m in the Peruvian Andes, North American natives (Na-Dene) from coastal British Columbia, and Caucasian North Americans. The frequencies of the alleles previously shown to be associated with increased fibrinogen levels were so low in the Quechuas that their presence could be accounted for solely by genetic admixture with Caucasians. Frequencies in the Na-Dene, a Native American group unrelated to the Quechua, were not significantly different from those in Caucasians. Am J Phys Anthropol 109:181–186, 1999. © 1999 Wiley-Liss, Inc." @default.
- W4256703886 created "2022-05-12" @default.
- W4256703886 creator A5006207744 @default.
- W4256703886 creator A5055349188 @default.
- W4256703886 creator A5062768335 @default.
- W4256703886 creator A5072305114 @default.
- W4256703886 date "1999-06-01" @default.
- W4256703886 modified "2023-09-26" @default.
- W4256703886 title "β‐fibrinogen allele frequencies in Peruvian Quechua, a high‐altitude native population" @default.
- W4256703886 doi "https://doi.org/10.1002/(sici)1096-8644(199906)109:2<181::aid-ajpa4>3.3.co;2-p" @default.
- W4256703886 hasPublicationYear "1999" @default.
- W4256703886 type Work @default.
- W4256703886 citedByCount "0" @default.
- W4256703886 crossrefType "journal-article" @default.
- W4256703886 hasAuthorship W4256703886A5006207744 @default.
- W4256703886 hasAuthorship W4256703886A5055349188 @default.
- W4256703886 hasAuthorship W4256703886A5062768335 @default.
- W4256703886 hasAuthorship W4256703886A5072305114 @default.
- W4256703886 hasConcept C104317684 @default.
- W4256703886 hasConcept C126322002 @default.
- W4256703886 hasConcept C134018914 @default.
- W4256703886 hasConcept C135763542 @default.
- W4256703886 hasConcept C144024400 @default.
- W4256703886 hasConcept C149923435 @default.
- W4256703886 hasConcept C168007829 @default.
- W4256703886 hasConcept C180754005 @default.
- W4256703886 hasConcept C2524010 @default.
- W4256703886 hasConcept C2776906770 @default.
- W4256703886 hasConcept C2779036427 @default.
- W4256703886 hasConcept C2780959883 @default.
- W4256703886 hasConcept C2908647359 @default.
- W4256703886 hasConcept C2994203641 @default.
- W4256703886 hasConcept C33923547 @default.
- W4256703886 hasConcept C37463918 @default.
- W4256703886 hasConcept C54355233 @default.
- W4256703886 hasConcept C55493867 @default.
- W4256703886 hasConcept C6350597 @default.
- W4256703886 hasConcept C71924100 @default.
- W4256703886 hasConcept C86803240 @default.
- W4256703886 hasConceptScore W4256703886C104317684 @default.
- W4256703886 hasConceptScore W4256703886C126322002 @default.
- W4256703886 hasConceptScore W4256703886C134018914 @default.
- W4256703886 hasConceptScore W4256703886C135763542 @default.
- W4256703886 hasConceptScore W4256703886C144024400 @default.
- W4256703886 hasConceptScore W4256703886C149923435 @default.
- W4256703886 hasConceptScore W4256703886C168007829 @default.
- W4256703886 hasConceptScore W4256703886C180754005 @default.
- W4256703886 hasConceptScore W4256703886C2524010 @default.
- W4256703886 hasConceptScore W4256703886C2776906770 @default.
- W4256703886 hasConceptScore W4256703886C2779036427 @default.
- W4256703886 hasConceptScore W4256703886C2780959883 @default.
- W4256703886 hasConceptScore W4256703886C2908647359 @default.
- W4256703886 hasConceptScore W4256703886C2994203641 @default.
- W4256703886 hasConceptScore W4256703886C33923547 @default.
- W4256703886 hasConceptScore W4256703886C37463918 @default.
- W4256703886 hasConceptScore W4256703886C54355233 @default.
- W4256703886 hasConceptScore W4256703886C55493867 @default.
- W4256703886 hasConceptScore W4256703886C6350597 @default.
- W4256703886 hasConceptScore W4256703886C71924100 @default.
- W4256703886 hasConceptScore W4256703886C86803240 @default.
- W4256703886 hasIssue "2" @default.
- W4256703886 hasLocation W42567038861 @default.
- W4256703886 hasOpenAccess W4256703886 @default.
- W4256703886 hasPrimaryLocation W42567038861 @default.
- W4256703886 hasRelatedWork W1974199321 @default.
- W4256703886 hasRelatedWork W1982270649 @default.
- W4256703886 hasRelatedWork W2034283276 @default.
- W4256703886 hasRelatedWork W2057739827 @default.
- W4256703886 hasRelatedWork W2103915008 @default.
- W4256703886 hasRelatedWork W2410204434 @default.
- W4256703886 hasRelatedWork W2418324446 @default.
- W4256703886 hasRelatedWork W290528026 @default.
- W4256703886 hasRelatedWork W3145896936 @default.
- W4256703886 hasRelatedWork W4256703886 @default.
- W4256703886 hasVolume "109" @default.
- W4256703886 isParatext "false" @default.
- W4256703886 isRetracted "false" @default.
- W4256703886 workType "article" @default.