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- W4256712912 abstract "Abstract Background Minor ailments are “self-limiting conditions which may be diagnosed and managed without a medical intervention”. A cluster randomised controlled trial (cRCT) was designed to evaluate the clinical, humanistic and economic outcomes of a Minor Ailment Service (MAS) in community pharmacy (CP) compared with usual care (UC). Methods The cRCT was conducted for six months from December 2017. The pharmacist-patient intervention consisted of a standardised face-to-face consultation on a web-based program using co-developed protocols, pharmacists’ training, practice change facilitators and patients’ educational material. Patients requesting a non-prescription medication (direct product request) or presenting minor ailments received MAS or UC and were followed-up by telephone 10-days after the consultation. The primary economic outcomes were incremental cost-effectiveness ratio (ICER) of the service and health related quality of life (HRQoL). Total costs included health system, CPs and patient direct costs: health professionals’ consultation time, medication costs, pharmacists’ training costs, investment of the pharmacy and consultation costs within the ten days following the initial consultation. The HRQoL was obtained using the EuroQoL 5D-5L at the time of the consultation and at 10-days follow up. A sensitivity analysis was carried out using bootstrapping. There were two sub-group analyses undertaken, for symptom presentation and direct product requests, to evaluate possible differences.Results A total of 808 patients (323 MAS and 485 UC) were recruited in 27 CPs with 42 pharmacists (20 MAS and 22 UC). 64.7% (n=523) of patients responded to follow-up after their consultation in CP. MAS patients gained an additional 0.0003 QALYs (p=0.053). When considering only MAS patients presenting with symptoms, the ICER was 24,733€/QALY with a 47.4% probability of cost-effectiveness (willingness to pay of 25,000€/QALY). Although when considering patients presenting for a direct product request, MAS was the dominant strategy with a 93.69% probability of cost-effectiveness.Conclusions Expanding community pharmacists’ scope through MAS may benefit health systems. To be fully cost effective, MAS should not only include consultations arising from symptom presentation but also include an oversight of self-selected products by patients. MAS increase patient safety through the appropriate use of non-prescription medication and through the direct referral of patients to GP.Trial registrationThe study was not registered but it was approved by the University of Granada Ethics Committee (approval number 331/CEIH/2017) and Xátiva-Ontinyent Ethics Committee “Lluís Alcanyís”." @default.
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- W4256712912 date "2020-10-23" @default.
- W4256712912 modified "2023-09-28" @default.
- W4256712912 title "A Cost Utility Analysis Alongside a Cluster Randomised Trial Evaluating a Minor Ailment Service Compared to Usual Care in Community Pharmacy" @default.
- W4256712912 doi "https://doi.org/10.21203/rs.3.rs-93288/v1" @default.
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