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- W4265987 abstract "Paul Langerhans first described the epidermal cell which now bears his name in 1868.1 It was not until 1973 that the first evidence for the involvement of Langerhans cells (LC) in antigen presentation was published.2 Since then it has become recognized that they represent a crucial component of the peripheral immune system. Electron microscopic analysis of LC demonstrated that they possess a lobulated, frequently convoluted nucleus, a clear cytoplasm with rough endoplasmic reticulum and a well developed Golgi apparatus, devoid of tonofilaments, desmosomes and melanosomes. Their most distinctive feature at the ultrastructural level, however, is the presence of a cytoplasmic organelle with a rod-or tennis racket-like structure, the Birbeck granule (BG).3" @default.
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- W4265987 date "1995-01-01" @default.
- W4265987 modified "2023-10-15" @default.
- W4265987 title "Immunoelectron Microscopic Analysis of Major Histocompatibility Class II Expression on Human Epidermal Langerhans Cells" @default.
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- W4265987 doi "https://doi.org/10.1007/978-3-662-22497-7_5" @default.
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