FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W42779042> ?p ?o ?g. }

• W42779042 endingPage "219" @default.
• W42779042 startingPage "189" @default.
• W42779042 abstract "Immunoglobulin (Ig) classes (in mammals, IgM, IgA, IgD, IgG, IgE) are defined by the isotypes of heavy (H) chains (µ, α, δ, γ, and ε). Each isotype is in turn distinguished by unique structures in its constant region domains. These different structures confer distinctive functions on the Ig classes. When two or more Ig classes are very similar, as occurs with the four different types of IgG found in man and mouse, they are usually termed subclasses. Each isotype is encoded by a distinct gene and multiple heavy chain isoforms can be produced by alternative pathways of RNA processing, such as the secreted (slg) and membrane (mlg) forms of all H chains, or the full-length and truncated H chain isoforms of certain avian antibodies. Allelic variation in the constant (C) regions gives rise to allotypes. The different types of light (L) chains (in mammals, к and λ) are also typically referred to as isotypes. This system of classification of Igs was developed from studies of man and his immunological understudy, the mouse, and has proven useful not only in these two species, but also in other mammalian species. Although the classification of mammalian Ig classes and isotypes is quite clear, the situation with Igs from nonmammalian vertebrates is not. For example, is the shark molecule referred to as IgM really IgM? Should we call the predominant low molecular weight Ig in chickens IgG or IgY? This chapter discusses the ways in which these and similar questions have been approached." @default.
• W42779042 created "2016-06-24" @default.
• W42779042 creator A5008659039 @default.
• W42779042 creator A5020065618 @default.
• W42779042 creator A5028972065 @default.
• W42779042 creator A5033610162 @default.
• W42779042 creator A5054791894 @default.
• W42779042 creator A5082688759 @default.
• W42779042 date "2000-01-01" @default.
• W42779042 modified "2023-10-06" @default.
• W42779042 title "Immunoglobulin Isotypes: Structure, Function, and Genetics" @default.
• W42779042 cites W1016546697 @default.
• W42779042 cites W113753478 @default.
• W42779042 cites W118227268 @default.
• W42779042 cites W147938112 @default.
• W42779042 cites W1487826363 @default.
• W42779042 cites W1490144752 @default.
• W42779042 cites W1510367500 @default.
• W42779042 cites W1513613763 @default.
• W42779042 cites W1525973486 @default.
• W42779042 cites W1540638614 @default.
• W42779042 cites W1541707585 @default.
• W42779042 cites W1558467261 @default.
• W42779042 cites W1577237226 @default.
• W42779042 cites W1590773291 @default.
• W42779042 cites W1596234512 @default.
• W42779042 cites W1631870832 @default.
• W42779042 cites W1665022174 @default.
• W42779042 cites W1744788824 @default.
• W42779042 cites W1766348490 @default.
• W42779042 cites W1796828658 @default.
• W42779042 cites W1830365590 @default.
• W42779042 cites W1840824980 @default.
• W42779042 cites W1841497788 @default.
• W42779042 cites W1919722157 @default.
• W42779042 cites W1921732610 @default.
• W42779042 cites W1922210072 @default.
• W42779042 cites W1942404939 @default.
• W42779042 cites W1964538987 @default.
• W42779042 cites W1969827334 @default.
• W42779042 cites W1970541248 @default.
• W42779042 cites W1974257409 @default.
• W42779042 cites W1978001540 @default.
• W42779042 cites W1981293520 @default.
• W42779042 cites W1984508840 @default.
• W42779042 cites W1984915911 @default.
• W42779042 cites W1987229882 @default.
• W42779042 cites W1992850719 @default.
• W42779042 cites W1993302019 @default.
• W42779042 cites W1994159495 @default.
• W42779042 cites W1997713447 @default.
• W42779042 cites W1999959730 @default.
• W42779042 cites W2000740251 @default.
• W42779042 cites W2004605196 @default.
• W42779042 cites W2005869248 @default.
• W42779042 cites W2008062906 @default.
• W42779042 cites W2008546779 @default.
• W42779042 cites W2013139631 @default.
• W42779042 cites W2023766068 @default.
• W42779042 cites W2024124488 @default.
• W42779042 cites W2025490928 @default.
• W42779042 cites W2025668260 @default.
• W42779042 cites W2027404992 @default.
• W42779042 cites W2030724279 @default.
• W42779042 cites W2032724606 @default.
• W42779042 cites W2035314845 @default.
• W42779042 cites W2035902011 @default.
• W42779042 cites W2036086075 @default.
• W42779042 cites W2037149962 @default.
• W42779042 cites W2037257193 @default.
• W42779042 cites W2038334022 @default.
• W42779042 cites W2039428314 @default.
• W42779042 cites W2039984371 @default.
• W42779042 cites W2040720915 @default.
• W42779042 cites W2041557519 @default.
• W42779042 cites W2041916747 @default.
• W42779042 cites W2044066005 @default.
• W42779042 cites W2044103083 @default.
• W42779042 cites W2045814424 @default.
• W42779042 cites W2047392488 @default.
• W42779042 cites W2047554700 @default.
• W42779042 cites W2048384613 @default.
• W42779042 cites W2049028980 @default.
• W42779042 cites W2050374131 @default.
• W42779042 cites W2051113765 @default.
• W42779042 cites W2051862080 @default.
• W42779042 cites W2052138908 @default.
• W42779042 cites W2052143929 @default.
• W42779042 cites W2053371575 @default.
• W42779042 cites W2054220682 @default.
• W42779042 cites W2054313572 @default.
• W42779042 cites W2060325623 @default.
• W42779042 cites W2060965517 @default.
• W42779042 cites W2063272862 @default.
• W42779042 cites W2066197804 @default.
• W42779042 cites W2067326574 @default.
• W42779042 cites W2068228216 @default.
• W42779042 cites W2071353036 @default.

• next