FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280490176> ?p ?o ?g. }

• W4280490176 endingPage "405" @default.
• W4280490176 startingPage "393" @default.
• W4280490176 abstract "Wild-type transthyretin amyloidosis (ATTRwt amyloidosis) is a progressive disease resulting from the accumulation of wild-type transthyretin (TTR) amyloid fibrils, and is diagnosed primarily in males. This analysis examined sex differences in patients with ATTRwt amyloidosis from the Transthyretin Amyloidosis Outcomes Survey (THAOS). THAOS is an ongoing, global, longitudinal, observational survey of patients with transthyretin amyloidosis, including both inherited and wild-type disease, and asymptomatic carriers of TTR mutations. THAOS data were analyzed to identify potential differences in demographic and clinical characteristics between males and females with ATTRwt amyloidosis (data cutoff: August 1, 2021). Of 1386 patients with ATTRwt amyloidosis, 84 (6%) were female and 1302 (94%) were male. Females had a higher median age at enrollment (80 vs. 78 years; p = 0.002) and symptom onset (75 vs. 73 years; p = 0.045) than males. Mean left ventricular (LV) ejection fraction was higher (53% vs. 48%; p = 0.001) and mean LV diastolic diameter lower (42 vs. 46 mm; p < 0.001) in females versus males, but sex was not identified as a predictor of LV mean wall thickness adjusted for height (beta coefficient − 0.22; p = 0.460) or a predominantly cardiac phenotype (odds ratio 1.60; p = 0.191). Modified polyneuropathy disability scores differed between groups (p < 0.001), with a larger proportion of scores ≥ IIIa among females (23% vs. 7%). Females with ATTRwt amyloidosis in THAOS tended to present at a later age and showed signs of less severe cardiac impairment and more severe walking impairment. ClinicalTrials.gov: NCT00628745." @default.
• W4280490176 created "2022-05-22" @default.
• W4280490176 creator A5011814572 @default.
• W4280490176 creator A5037555349 @default.
• W4280490176 creator A5049409439 @default.
• W4280490176 creator A5057426360 @default.
• W4280490176 creator A5059417970 @default.
• W4280490176 creator A5062816598 @default.
• W4280490176 creator A5067374670 @default.
• W4280490176 creator A5070359355 @default.
• W4280490176 creator A5072502164 @default.
• W4280490176 creator A5072877047 @default.
• W4280490176 creator A5079224143 @default.
• W4280490176 creator A5080366556 @default.
• W4280490176 date "2022-05-18" @default.
• W4280490176 modified "2023-10-09" @default.
• W4280490176 title "Sex Differences in Wild-Type Transthyretin Amyloidosis: An Analysis from the Transthyretin Amyloidosis Outcomes Survey (THAOS)" @default.
• W4280490176 cites W1964853598 @default.
• W4280490176 cites W2020106206 @default.
• W4280490176 cites W2076492105 @default.
• W4280490176 cites W2115862827 @default.
• W4280490176 cites W2118369819 @default.
• W4280490176 cites W2509971241 @default.
• W4280490176 cites W2594063085 @default.
• W4280490176 cites W2727583207 @default.
• W4280490176 cites W2752808157 @default.
• W4280490176 cites W2755151577 @default.
• W4280490176 cites W2757242206 @default.
• W4280490176 cites W2766043255 @default.
• W4280490176 cites W2927665182 @default.
• W4280490176 cites W2948364217 @default.
• W4280490176 cites W2960721446 @default.
• W4280490176 cites W3001354239 @default.
• W4280490176 cites W3049142765 @default.
• W4280490176 cites W3052126902 @default.
• W4280490176 cites W3113150215 @default.
• W4280490176 cites W3173766242 @default.
• W4280490176 cites W3187296608 @default.
• W4280490176 cites W4206084380 @default.
• W4280490176 doi "https://doi.org/10.1007/s40119-022-00265-7" @default.
• W4280490176 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35583798" @default.
• W4280490176 hasPublicationYear "2022" @default.
• W4280490176 type Work @default.
• W4280490176 citedByCount "5" @default.
• W4280490176 countsByYear W42804901762022 @default.
• W4280490176 countsByYear W42804901762023 @default.
• W4280490176 crossrefType "journal-article" @default.
• W4280490176 hasAuthorship W4280490176A5011814572 @default.
• W4280490176 hasAuthorship W4280490176A5037555349 @default.
• W4280490176 hasAuthorship W4280490176A5049409439 @default.
• W4280490176 hasAuthorship W4280490176A5057426360 @default.
• W4280490176 hasAuthorship W4280490176A5059417970 @default.
• W4280490176 hasAuthorship W4280490176A5062816598 @default.
• W4280490176 hasAuthorship W4280490176A5067374670 @default.
• W4280490176 hasAuthorship W4280490176A5070359355 @default.
• W4280490176 hasAuthorship W4280490176A5072502164 @default.
• W4280490176 hasAuthorship W4280490176A5072877047 @default.
• W4280490176 hasAuthorship W4280490176A5079224143 @default.
• W4280490176 hasAuthorship W4280490176A5080366556 @default.
• W4280490176 hasBestOaLocation W42804901761 @default.
• W4280490176 hasConcept C121157162 @default.
• W4280490176 hasConcept C126322002 @default.
• W4280490176 hasConcept C134018914 @default.
• W4280490176 hasConcept C142724271 @default.
• W4280490176 hasConcept C164705383 @default.
• W4280490176 hasConcept C2777607188 @default.
• W4280490176 hasConcept C2777633098 @default.
• W4280490176 hasConcept C2777910003 @default.
• W4280490176 hasConcept C2778198053 @default.
• W4280490176 hasConcept C2779951007 @default.
• W4280490176 hasConcept C71924100 @default.
• W4280490176 hasConcept C78085059 @default.
• W4280490176 hasConcept C90924648 @default.
• W4280490176 hasConceptScore W4280490176C121157162 @default.
• W4280490176 hasConceptScore W4280490176C126322002 @default.
• W4280490176 hasConceptScore W4280490176C134018914 @default.
• W4280490176 hasConceptScore W4280490176C142724271 @default.
• W4280490176 hasConceptScore W4280490176C164705383 @default.
• W4280490176 hasConceptScore W4280490176C2777607188 @default.
• W4280490176 hasConceptScore W4280490176C2777633098 @default.
• W4280490176 hasConceptScore W4280490176C2777910003 @default.
• W4280490176 hasConceptScore W4280490176C2778198053 @default.
• W4280490176 hasConceptScore W4280490176C2779951007 @default.
• W4280490176 hasConceptScore W4280490176C71924100 @default.
• W4280490176 hasConceptScore W4280490176C78085059 @default.
• W4280490176 hasConceptScore W4280490176C90924648 @default.
• W4280490176 hasFunder F4320307765 @default.
• W4280490176 hasIssue "3" @default.
• W4280490176 hasLocation W42804901761 @default.
• W4280490176 hasLocation W42804901762 @default.
• W4280490176 hasLocation W42804901763 @default.
• W4280490176 hasLocation W42804901764 @default.
• W4280490176 hasOpenAccess W4280490176 @default.
• W4280490176 hasPrimaryLocation W42804901761 @default.
• W4280490176 hasRelatedWork W1994398638 @default.
• W4280490176 hasRelatedWork W2057327705 @default.
• W4280490176 hasRelatedWork W2112429383 @default.
• W4280490176 hasRelatedWork W2624652407 @default.

• next