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• W4280490946 abstract "BackgroundMyocardial injury after non-cardiac surgery (MINS) is associated with increased mortality and major adverse cardiac events (MACE). The utility of MINS after solid-organ transplantation is not well established.MethodsWe performed a retrospective review of consecutive patients between 2015-2019 undergoing liver or kidney transplantation at a tertiary transplant center with troponins drawn within 30 days of transplantation. Patients who had normal troponin levels within were included in the non-MINS group. Those with elevated troponin (>0.11 ng/mL) were included in the MINS group. The primary outcome was MACE; defined as death, myocardial infarction, coronary revascularization, stroke or heart failure hospitalization.ResultsA total of 112 patients were included in the analysis. Fifty-eight (51.7%) and 54 (48.3%) patients received liver and kidney transplants, respectively. Mean follow up was 3 ± 1.3 years. Sixteen patients (14.2%) in the MINS group developed MACE, including 11 (9.8%) within one-year (adjusted hazard ratio 10.4, 95% Confidence Interval 1.8 – 198, Table 4). Kaplan-Meier cumulative MACE was significantly higher in the MINS group (p = 0.03, Figure 1).ConclusionsDisclosuresR. Waksman: Abbott: Advisory Board/Board Member and Consulting; AstraZeneca: Speaker Bureau; Biotronik: Consulting; Boston Scientific Corp.: Advisory Board/Board Member and Consulting; Cordis: Consulting; MedAlliance: Investor; Medtronic: Advisory Board/Board Member and Consulting; Philips: Advisory Board/Board Member and Consulting; Pi-Cardia LTD: Advisory Board/Board Member and Consulting; Swiss Interventional Systems / Sis Medical AG: Consulting; Transmural Systems, Inc.: Consulting; Venous MedTech: Consulting; S. Kumar Nothing to disclose. B. C. Case Nothing to disclose. M. Yang Nothing to disclose. Z. Qamer Nothing to disclose. R. Satoskar Nothing to disclose. A. Hill Nothing to disclose. I. Ben-Dor Nothing to disclose. BackgroundMyocardial injury after non-cardiac surgery (MINS) is associated with increased mortality and major adverse cardiac events (MACE). The utility of MINS after solid-organ transplantation is not well established. Myocardial injury after non-cardiac surgery (MINS) is associated with increased mortality and major adverse cardiac events (MACE). The utility of MINS after solid-organ transplantation is not well established. MethodsWe performed a retrospective review of consecutive patients between 2015-2019 undergoing liver or kidney transplantation at a tertiary transplant center with troponins drawn within 30 days of transplantation. Patients who had normal troponin levels within were included in the non-MINS group. Those with elevated troponin (>0.11 ng/mL) were included in the MINS group. The primary outcome was MACE; defined as death, myocardial infarction, coronary revascularization, stroke or heart failure hospitalization. We performed a retrospective review of consecutive patients between 2015-2019 undergoing liver or kidney transplantation at a tertiary transplant center with troponins drawn within 30 days of transplantation. Patients who had normal troponin levels within were included in the non-MINS group. Those with elevated troponin (>0.11 ng/mL) were included in the MINS group. The primary outcome was MACE; defined as death, myocardial infarction, coronary revascularization, stroke or heart failure hospitalization. ResultsA total of 112 patients were included in the analysis. Fifty-eight (51.7%) and 54 (48.3%) patients received liver and kidney transplants, respectively. Mean follow up was 3 ± 1.3 years. Sixteen patients (14.2%) in the MINS group developed MACE, including 11 (9.8%) within one-year (adjusted hazard ratio 10.4, 95% Confidence Interval 1.8 – 198, Table 4). Kaplan-Meier cumulative MACE was significantly higher in the MINS group (p = 0.03, Figure 1). A total of 112 patients were included in the analysis. Fifty-eight (51.7%) and 54 (48.3%) patients received liver and kidney transplants, respectively. Mean follow up was 3 ± 1.3 years. Sixteen patients (14.2%) in the MINS group developed MACE, including 11 (9.8%) within one-year (adjusted hazard ratio 10.4, 95% Confidence Interval 1.8 – 198, Table 4). Kaplan-Meier cumulative MACE was significantly higher in the MINS group (p = 0.03, Figure 1). Conclusions DisclosuresR. Waksman: Abbott: Advisory Board/Board Member and Consulting; AstraZeneca: Speaker Bureau; Biotronik: Consulting; Boston Scientific Corp.: Advisory Board/Board Member and Consulting; Cordis: Consulting; MedAlliance: Investor; Medtronic: Advisory Board/Board Member and Consulting; Philips: Advisory Board/Board Member and Consulting; Pi-Cardia LTD: Advisory Board/Board Member and Consulting; Swiss Interventional Systems / Sis Medical AG: Consulting; Transmural Systems, Inc.: Consulting; Venous MedTech: Consulting; S. Kumar Nothing to disclose. B. C. Case Nothing to disclose. M. Yang Nothing to disclose. Z. Qamer Nothing to disclose. R. Satoskar Nothing to disclose. A. Hill Nothing to disclose. I. Ben-Dor Nothing to disclose. R. Waksman: Abbott: Advisory Board/Board Member and Consulting; AstraZeneca: Speaker Bureau; Biotronik: Consulting; Boston Scientific Corp.: Advisory Board/Board Member and Consulting; Cordis: Consulting; MedAlliance: Investor; Medtronic: Advisory Board/Board Member and Consulting; Philips: Advisory Board/Board Member and Consulting; Pi-Cardia LTD: Advisory Board/Board Member and Consulting; Swiss Interventional Systems / Sis Medical AG: Consulting; Transmural Systems, Inc.: Consulting; Venous MedTech: Consulting; S. Kumar Nothing to disclose. B. C. Case Nothing to disclose. M. Yang Nothing to disclose. Z. Qamer Nothing to disclose. R. Satoskar Nothing to disclose. A. Hill Nothing to disclose. I. Ben-Dor Nothing to disclose." @default.
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• W4280490946 title "B-24 | Post-Operative Myocardial Injury and Outcomes in Solid-Organ Transplant Recipients" @default.
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