FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280491489> ?p ?o ?g. }

• W4280491489 endingPage "383" @default.
• W4280491489 startingPage "377" @default.
• W4280491489 abstract "Objectives: To investigate ocular surface alterations and in vivo confocal microscopic characteristics of the cornea in dry eye disease (DED) with contact lens wear (CLW). Methods: Sixty participants were divided into three groups: DED with CLW (n=20), DED without CLW (n=20), and normal control (n=20). Ocular surface parameters were evaluated. Basal tears and in vivo confocal microscopy images of the cornea were collected. Multiplex bead analysis was used to assess interleukin (IL)-6, IL-1β, tumor necrosis factor (TNF)-α, nerve growth factor (NGF), and substance P (SP) in tears. Nerve morphology and dendritic cell density in corneal subbasal nerve images were calculated. Results: The DED with CLW group showed significantly higher ocular surface staining scores ( P =0.022) and higher levels of IL-1β, NGF, and SP in tears ( P =0.014, P =0.004 and P =0.025) than the DED without CLW group. Corneal dendritic cell density in the DED with CLW group was significantly higher than that in the normal controls ( P =0.001) and DED without CLW group ( P =0.043). Tear cytokine levels of IL-1β, NGF, and SP were correlated with ocular surface parameters in the DED with CLW group. Moreover, the years of CLW were positively correlated with corneal dendritic cell density (r=0.527, P =0.017) and negatively correlated with corneal nerve density (r=−0.511, P =0.021). Conclusions: Patients with DED with CLW showed greater epithelial damage, elevated inflammatory cytokines and neuromediators in tears, and higher corneal dendritic cell density than patients with DED without CLW. The immune and nervous systems may be involved in contact lens–related DED." @default.
• W4280491489 created "2022-05-22" @default.
• W4280491489 creator A5001238406 @default.
• W4280491489 creator A5015137143 @default.
• W4280491489 creator A5031059583 @default.
• W4280491489 creator A5033160869 @default.
• W4280491489 creator A5049777389 @default.
• W4280491489 creator A5057905491 @default.
• W4280491489 creator A5058861603 @default.
• W4280491489 creator A5065745300 @default.
• W4280491489 date "2022-05-17" @default.
• W4280491489 modified "2023-10-16" @default.
• W4280491489 title "Evaluation of Ocular Surface Characteristics in Dry Eye Disease With and Without Soft Contact Lens Wear: A Comparative Study" @default.
• W4280491489 cites W1979705469 @default.
• W4280491489 cites W1984557396 @default.
• W4280491489 cites W2000567562 @default.
• W4280491489 cites W2003282708 @default.
• W4280491489 cites W2009265116 @default.
• W4280491489 cites W2009713241 @default.
• W4280491489 cites W2020624195 @default.
• W4280491489 cites W2022109868 @default.
• W4280491489 cites W2034210776 @default.
• W4280491489 cites W2038656522 @default.
• W4280491489 cites W2052808939 @default.
• W4280491489 cites W2057754382 @default.
• W4280491489 cites W2065889380 @default.
• W4280491489 cites W2071899418 @default.
• W4280491489 cites W2074616243 @default.
• W4280491489 cites W2095336651 @default.
• W4280491489 cites W2108414140 @default.
• W4280491489 cites W2108661738 @default.
• W4280491489 cites W2120743048 @default.
• W4280491489 cites W2184608505 @default.
• W4280491489 cites W2327948963 @default.
• W4280491489 cites W2335839765 @default.
• W4280491489 cites W2442224165 @default.
• W4280491489 cites W2474156261 @default.
• W4280491489 cites W2548426831 @default.
• W4280491489 cites W2597804265 @default.
• W4280491489 cites W2739359388 @default.
• W4280491489 cites W2743670010 @default.
• W4280491489 cites W2887105864 @default.
• W4280491489 cites W2890648071 @default.
• W4280491489 cites W2917541098 @default.
• W4280491489 cites W2944627500 @default.
• W4280491489 cites W2980095270 @default.
• W4280491489 cites W2996579247 @default.
• W4280491489 cites W3007796292 @default.
• W4280491489 cites W3085870433 @default.
• W4280491489 cites W3162906591 @default.
• W4280491489 cites W3170686328 @default.
• W4280491489 cites W4253760541 @default.
• W4280491489 doi "https://doi.org/10.1097/icl.0000000000000904" @default.
• W4280491489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35583308" @default.
• W4280491489 hasPublicationYear "2022" @default.
• W4280491489 type Work @default.
• W4280491489 citedByCount "4" @default.
• W4280491489 countsByYear W42804914892023 @default.
• W4280491489 crossrefType "journal-article" @default.
• W4280491489 hasAuthorship W4280491489A5001238406 @default.
• W4280491489 hasAuthorship W4280491489A5015137143 @default.
• W4280491489 hasAuthorship W4280491489A5031059583 @default.
• W4280491489 hasAuthorship W4280491489A5033160869 @default.
• W4280491489 hasAuthorship W4280491489A5049777389 @default.
• W4280491489 hasAuthorship W4280491489A5057905491 @default.
• W4280491489 hasAuthorship W4280491489A5058861603 @default.
• W4280491489 hasAuthorship W4280491489A5065745300 @default.
• W4280491489 hasConcept C105702510 @default.
• W4280491489 hasConcept C118487528 @default.
• W4280491489 hasConcept C120665830 @default.
• W4280491489 hasConcept C121332964 @default.
• W4280491489 hasConcept C126322002 @default.
• W4280491489 hasConcept C136009344 @default.
• W4280491489 hasConcept C142724271 @default.
• W4280491489 hasConcept C150903083 @default.
• W4280491489 hasConcept C170493617 @default.
• W4280491489 hasConcept C185592680 @default.
• W4280491489 hasConcept C203014093 @default.
• W4280491489 hasConcept C207001950 @default.
• W4280491489 hasConcept C2776882836 @default.
• W4280491489 hasConcept C2778275304 @default.
• W4280491489 hasConcept C2778423431 @default.
• W4280491489 hasConcept C2986805488 @default.
• W4280491489 hasConcept C71924100 @default.
• W4280491489 hasConcept C86803240 @default.
• W4280491489 hasConceptScore W4280491489C105702510 @default.
• W4280491489 hasConceptScore W4280491489C118487528 @default.
• W4280491489 hasConceptScore W4280491489C120665830 @default.
• W4280491489 hasConceptScore W4280491489C121332964 @default.
• W4280491489 hasConceptScore W4280491489C126322002 @default.
• W4280491489 hasConceptScore W4280491489C136009344 @default.
• W4280491489 hasConceptScore W4280491489C142724271 @default.
• W4280491489 hasConceptScore W4280491489C150903083 @default.
• W4280491489 hasConceptScore W4280491489C170493617 @default.
• W4280491489 hasConceptScore W4280491489C185592680 @default.
• W4280491489 hasConceptScore W4280491489C203014093 @default.
• W4280491489 hasConceptScore W4280491489C207001950 @default.
• W4280491489 hasConceptScore W4280491489C2776882836 @default.

• next